Keratoconjunctivitis sicca with associated secondary uveitis elicited in rats after systemic xylazine/ketamine anesthesia

The systemic administration of an anesthetic dosage of a combination of xylazine and ketamine hydrochloride produced an acute exposure keratopathy which progressed into a syndrome resembling keratoconjunctivitis sicca. Within a few minutes corneal changes occurred that were characterized by viscous...

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Veröffentlicht in:	Experimental eye research 1989-11, Vol.49 (5), p.861-871
Hauptverfasser:	Kufoy, Ernesto A., Pakalnis, Vytautas A., Parks, Cheryl D., Wells, Alvin, Yang, Chang-Hsu, Fox, Alvin
Format:	Artikel
Sprache:	eng
Schlagworte:	anesthesia Animals Biological and medical sciences cataracts cornea Diseases of cornea, anterior segment and sclera Female Keratoconjunctivitis - chemically induced keratoconjunctivitis sicca Keratoconjunctivitis Sicca - chemically induced ketamine Ketamine - adverse effects Medical sciences Ophthalmology pentobarbital Rats Rats, Inbred Lew Thiazines - adverse effects uveitis Uveitis, Anterior - chemically induced xylazine Xylazine - adverse effects
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