Tardive Dyskinesia in Psychiatric Patients with Substance Use Disorders
The authors report on the incidence of tardive dyskinesia (TD) in a sample of 284 psychiatric patients who chronically abused street drugs; 82.4% had received neuroleptic treatment for the length of their illness (10.5 ± 5.8 years). The incidence of TD was 15.9%. The incidence of TD was significantl...
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| Veröffentlicht in: | The American journal of drug and alcohol abuse 1990, Vol.16 (1-2), p.57-66 |
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| container_title | The American journal of drug and alcohol abuse |
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| creator | On vera, Arturo A. Kiefer, Mary Mary Manley, Norlee |
| description | The authors report on the incidence of tardive dyskinesia (TD) in a sample of 284 psychiatric patients who chronically abused street drugs; 82.4% had received neuroleptic treatment for the length of their illness (10.5 ± 5.8 years). The incidence of TD was 15.9%. The incidence of TD was significantly higher in groups of patients in which alcohol alone (25.4%) or in combination with cannabis (26.7 %) was the drug of abuse than in those groups in which alcohol was either absent or used in combination with sedatives, opioids, or stimulants. Tardive dyskinesia was absent in patients not treated with neuroleptics and in a control group of drug abusers free of mental disorders. The anatomical distribution was similar to that reported in other psychiatric samples. Mean severity was mild and incapacitation and distress were minimal. Polydrug abuse was dominant in both patients and controls, and alcohol abuse was more |
| doi_str_mv | 10.3109/00952999009001572 |
| format | Article |
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The incidence of TD was 15.9%. The incidence of TD was significantly higher in groups of patients in which alcohol alone (25.4%) or in combination with cannabis (26.7 %) was the drug of abuse than in those groups in which alcohol was either absent or used in combination with sedatives, opioids, or stimulants. Tardive dyskinesia was absent in patients not treated with neuroleptics and in a control group of drug abusers free of mental disorders. The anatomical distribution was similar to that reported in other psychiatric samples. Mean severity was mild and incapacitation and distress were minimal. 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The incidence of TD was 15.9%. The incidence of TD was significantly higher in groups of patients in which alcohol alone (25.4%) or in combination with cannabis (26.7 %) was the drug of abuse than in those groups in which alcohol was either absent or used in combination with sedatives, opioids, or stimulants. Tardive dyskinesia was absent in patients not treated with neuroleptics and in a control group of drug abusers free of mental disorders. The anatomical distribution was similar to that reported in other psychiatric samples. Mean severity was mild and incapacitation and distress were minimal. Polydrug abuse was dominant in both patients and controls, and alcohol abuse was more</description><subject>Adult</subject><subject>Affective Disorders, Psychotic - drug therapy</subject><subject>Alcoholism - complications</subject><subject>Antipsychotic Agents - adverse effects</subject><subject>Biological and medical sciences</subject><subject>Dyskinesia, Drug-Induced - etiology</subject><subject>Female</subject><subject>Humans</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Nervous system (semeiology, syndromes)</subject><subject>Nervous system as a whole</subject><subject>Neurology</subject><subject>Psychotic Disorders - complications</subject><subject>Psychotic Disorders - drug therapy</subject><subject>Psychotropic Drugs - adverse effects</subject><subject>Risk Factors</subject><subject>Schizophrenia - drug therapy</subject><subject>Substance-Related Disorders - complications</subject><issn>0095-2990</issn><issn>1097-9891</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1990</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kE1LAzEQhoMotVZ_gAdhD-JtNdnPBL1I_YSCBfW8zGYTmrrdrZmsZf-9Ka2KCJ4G8j7vMHkIOWb0PGZUXFAq0kgI4SelLM2jHTL073kouGC7ZLjOQw_QfXKAOKce4nkyIAMmcpqkbEjuX8BW5kMFNz2-mUahgcA0wRR7OTPgrJHBFJxRjcNgZdwseO5KdNBIFbyibxlsbaUsHpI9DTWqo-0ckde725fxQzh5un8cX09CmWTMhVqXEZdVzqUqc55mmdBpTlPQ_ugk1aLMsjiuOBWaRZEAYEmUgOKS0jyiqSjjETnb7F3a9r1T6IqFQanqGhrVdlh4CYLHLPMg24DStohW6WJpzQJsXzBarOUVf-T5zsl2eVcuVPXT2Njy-ek2B5RQa-s9GPzGMs4zyoTHrjaYaXRrF7BqbV0VDvq6tV-d-L8rLn_VZwpqN5NgVTFvO9t4vf_84RPI6pr8</recordid><startdate>1990</startdate><enddate>1990</enddate><creator>On vera, Arturo A.</creator><creator>Kiefer, Mary Mary</creator><creator>Manley, Norlee</creator><general>Informa UK Ltd</general><general>Taylor & Francis</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7U7</scope><scope>C1K</scope></search><sort><creationdate>1990</creationdate><title>Tardive Dyskinesia in Psychiatric Patients with Substance Use Disorders</title><author>On vera, Arturo A. ; Kiefer, Mary Mary ; Manley, Norlee</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c461t-ffb28cd78ceb785669f5705af09745f9b6633d809f1229aa1424ae8c0072059b3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1990</creationdate><topic>Adult</topic><topic>Affective Disorders, Psychotic - drug therapy</topic><topic>Alcoholism - complications</topic><topic>Antipsychotic Agents - adverse effects</topic><topic>Biological and medical sciences</topic><topic>Dyskinesia, Drug-Induced - etiology</topic><topic>Female</topic><topic>Humans</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Nervous system (semeiology, syndromes)</topic><topic>Nervous system as a whole</topic><topic>Neurology</topic><topic>Psychotic Disorders - complications</topic><topic>Psychotic Disorders - drug therapy</topic><topic>Psychotropic Drugs - adverse effects</topic><topic>Risk Factors</topic><topic>Schizophrenia - drug therapy</topic><topic>Substance-Related Disorders - complications</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>On vera, Arturo A.</creatorcontrib><creatorcontrib>Kiefer, Mary Mary</creatorcontrib><creatorcontrib>Manley, Norlee</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Toxicology Abstracts</collection><collection>Environmental Sciences and Pollution Management</collection><jtitle>The American journal of drug and alcohol abuse</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>On vera, Arturo A.</au><au>Kiefer, Mary Mary</au><au>Manley, Norlee</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Tardive Dyskinesia in Psychiatric Patients with Substance Use Disorders</atitle><jtitle>The American journal of drug and alcohol abuse</jtitle><addtitle>Am J Drug Alcohol Abuse</addtitle><date>1990</date><risdate>1990</risdate><volume>16</volume><issue>1-2</issue><spage>57</spage><epage>66</epage><pages>57-66</pages><issn>0095-2990</issn><eissn>1097-9891</eissn><coden>AJDABD</coden><abstract>The authors report on the incidence of tardive dyskinesia (TD) in a sample of 284 psychiatric patients who chronically abused street drugs; 82.4% had received neuroleptic treatment for the length of their illness (10.5 ± 5.8 years). The incidence of TD was 15.9%. The incidence of TD was significantly higher in groups of patients in which alcohol alone (25.4%) or in combination with cannabis (26.7 %) was the drug of abuse than in those groups in which alcohol was either absent or used in combination with sedatives, opioids, or stimulants. Tardive dyskinesia was absent in patients not treated with neuroleptics and in a control group of drug abusers free of mental disorders. The anatomical distribution was similar to that reported in other psychiatric samples. Mean severity was mild and incapacitation and distress were minimal. Polydrug abuse was dominant in both patients and controls, and alcohol abuse was more</abstract><cop>Colchester</cop><pub>Informa UK Ltd</pub><pmid>1970451</pmid><doi>10.3109/00952999009001572</doi><tpages>10</tpages></addata></record> |
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| ispartof | The American journal of drug and alcohol abuse, 1990, Vol.16 (1-2), p.57-66 |
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| source | Taylor & Francis; MEDLINE; Taylor & Francis Medical Library - CRKN |
| subjects | Adult Affective Disorders, Psychotic - drug therapy Alcoholism - complications Antipsychotic Agents - adverse effects Biological and medical sciences Dyskinesia, Drug-Induced - etiology Female Humans Male Medical sciences Nervous system (semeiology, syndromes) Nervous system as a whole Neurology Psychotic Disorders - complications Psychotic Disorders - drug therapy Psychotropic Drugs - adverse effects Risk Factors Schizophrenia - drug therapy Substance-Related Disorders - complications |
| title | Tardive Dyskinesia in Psychiatric Patients with Substance Use Disorders |
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