Effects of 1 alpha ,25-dihydroxyvitamin D sub(3) on the human chronic myelogenous leukemia cell line RWLeu-4

Effects of 1 alpha ,25-dihydroxyvitamin D sub(3) on the human chronic myelogenous leukemia cell line RWLeu-4

The effects of 1 alpha -25-dihydroxyvitamin D sub(3) (VD sub(3)) on proliferation, differentiation, and macromolecular synthesis in the new Philadelphia chromosome-positive chronic myelogenous leukemia cell line, RWLeu-4, were investigated. Because of the presence of a functional receptor-effector s...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Cancer research (Chicago, Ill.) Ill.), 1990-01, Vol.50 (10), p.3087-3094
Hauptverfasser: Lasky, SR, Bell, W, Huhn, R D, Posner, M R, Wiemann, M, Calabresi, P, Eil, C
Format: Artikel
Sprache:eng
Schlagworte:
chronic myeloid leukemia
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
container_end_page 3094
container_issue 10
container_start_page 3087
container_title Cancer research (Chicago, Ill.)
container_volume 50
creator Lasky, SR
Bell, W
Huhn, R D
Posner, M R
Wiemann, M
Calabresi, P
Eil, C
description The effects of 1 alpha -25-dihydroxyvitamin D sub(3) (VD sub(3)) on proliferation, differentiation, and macromolecular synthesis in the new Philadelphia chromosome-positive chronic myelogenous leukemia cell line, RWLeu-4, were investigated. Because of the presence of a functional receptor-effector system for VD sub(3) and multiple biological responses to the hormone, these cells provide a unique model system with which to probe the specific effects of VD sub(3) on cell growth and differentiation in chronic myelogenous leukemia.
format Article
fullrecord <record><control><sourceid>proquest</sourceid><recordid>TN_cdi_proquest_miscellaneous_15794170</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>15794170</sourcerecordid><originalsourceid>FETCH-proquest_miscellaneous_157941703</originalsourceid><addsrcrecordid>eNqNjMsKwjAUBbNQsD7-4a5EwUKiDdW1Vly4EsGlxHpronnUphH791bwA1wdBmZOh0SU0mXMk3TeI33v7y1yRnlEdFYUmNceXAEMhC6lgNmcx1clm2vl3s1L1cIoCxvw4TJZTMFZqCWCDEZYyGXlrMrBNKjdDa0LHjSGBxolIEetQSuLcDjtMcTJkHQLoT2Ofjsg4212XO_isnLPgL4-G-W_lbDYPp0ZT1cJS-nib_EDmiZJ1w</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>15794170</pqid></control><display><type>article</type><title>Effects of 1 alpha ,25-dihydroxyvitamin D sub(3) on the human chronic myelogenous leukemia cell line RWLeu-4</title><source>American Association for Cancer Research</source><source>EZB-FREE-00999 freely available EZB journals</source><creator>Lasky, SR ; Bell, W ; Huhn, R D ; Posner, M R ; Wiemann, M ; Calabresi, P ; Eil, C</creator><creatorcontrib>Lasky, SR ; Bell, W ; Huhn, R D ; Posner, M R ; Wiemann, M ; Calabresi, P ; Eil, C</creatorcontrib><description>The effects of 1 alpha -25-dihydroxyvitamin D sub(3) (VD sub(3)) on proliferation, differentiation, and macromolecular synthesis in the new Philadelphia chromosome-positive chronic myelogenous leukemia cell line, RWLeu-4, were investigated. Because of the presence of a functional receptor-effector system for VD sub(3) and multiple biological responses to the hormone, these cells provide a unique model system with which to probe the specific effects of VD sub(3) on cell growth and differentiation in chronic myelogenous leukemia.</description><identifier>ISSN: 0008-5472</identifier><language>eng</language><subject>chronic myeloid leukemia</subject><ispartof>Cancer research (Chicago, Ill.), 1990-01, Vol.50 (10), p.3087-3094</ispartof><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784</link.rule.ids></links><search><creatorcontrib>Lasky, SR</creatorcontrib><creatorcontrib>Bell, W</creatorcontrib><creatorcontrib>Huhn, R D</creatorcontrib><creatorcontrib>Posner, M R</creatorcontrib><creatorcontrib>Wiemann, M</creatorcontrib><creatorcontrib>Calabresi, P</creatorcontrib><creatorcontrib>Eil, C</creatorcontrib><title>Effects of 1 alpha ,25-dihydroxyvitamin D sub(3) on the human chronic myelogenous leukemia cell line RWLeu-4</title><title>Cancer research (Chicago, Ill.)</title><description>The effects of 1 alpha -25-dihydroxyvitamin D sub(3) (VD sub(3)) on proliferation, differentiation, and macromolecular synthesis in the new Philadelphia chromosome-positive chronic myelogenous leukemia cell line, RWLeu-4, were investigated. Because of the presence of a functional receptor-effector system for VD sub(3) and multiple biological responses to the hormone, these cells provide a unique model system with which to probe the specific effects of VD sub(3) on cell growth and differentiation in chronic myelogenous leukemia.</description><subject>chronic myeloid leukemia</subject><issn>0008-5472</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1990</creationdate><recordtype>article</recordtype><recordid>eNqNjMsKwjAUBbNQsD7-4a5EwUKiDdW1Vly4EsGlxHpronnUphH791bwA1wdBmZOh0SU0mXMk3TeI33v7y1yRnlEdFYUmNceXAEMhC6lgNmcx1clm2vl3s1L1cIoCxvw4TJZTMFZqCWCDEZYyGXlrMrBNKjdDa0LHjSGBxolIEetQSuLcDjtMcTJkHQLoT2Ofjsg4212XO_isnLPgL4-G-W_lbDYPp0ZT1cJS-nib_EDmiZJ1w</recordid><startdate>19900101</startdate><enddate>19900101</enddate><creator>Lasky, SR</creator><creator>Bell, W</creator><creator>Huhn, R D</creator><creator>Posner, M R</creator><creator>Wiemann, M</creator><creator>Calabresi, P</creator><creator>Eil, C</creator><scope>8FD</scope><scope>FR3</scope><scope>M7Z</scope><scope>P64</scope></search><sort><creationdate>19900101</creationdate><title>Effects of 1 alpha ,25-dihydroxyvitamin D sub(3) on the human chronic myelogenous leukemia cell line RWLeu-4</title><author>Lasky, SR ; Bell, W ; Huhn, R D ; Posner, M R ; Wiemann, M ; Calabresi, P ; Eil, C</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-proquest_miscellaneous_157941703</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1990</creationdate><topic>chronic myeloid leukemia</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Lasky, SR</creatorcontrib><creatorcontrib>Bell, W</creatorcontrib><creatorcontrib>Huhn, R D</creatorcontrib><creatorcontrib>Posner, M R</creatorcontrib><creatorcontrib>Wiemann, M</creatorcontrib><creatorcontrib>Calabresi, P</creatorcontrib><creatorcontrib>Eil, C</creatorcontrib><collection>Technology Research Database</collection><collection>Engineering Research Database</collection><collection>Biochemistry Abstracts 1</collection><collection>Biotechnology and BioEngineering Abstracts</collection><jtitle>Cancer research (Chicago, Ill.)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Lasky, SR</au><au>Bell, W</au><au>Huhn, R D</au><au>Posner, M R</au><au>Wiemann, M</au><au>Calabresi, P</au><au>Eil, C</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Effects of 1 alpha ,25-dihydroxyvitamin D sub(3) on the human chronic myelogenous leukemia cell line RWLeu-4</atitle><jtitle>Cancer research (Chicago, Ill.)</jtitle><date>1990-01-01</date><risdate>1990</risdate><volume>50</volume><issue>10</issue><spage>3087</spage><epage>3094</epage><pages>3087-3094</pages><issn>0008-5472</issn><abstract>The effects of 1 alpha -25-dihydroxyvitamin D sub(3) (VD sub(3)) on proliferation, differentiation, and macromolecular synthesis in the new Philadelphia chromosome-positive chronic myelogenous leukemia cell line, RWLeu-4, were investigated. Because of the presence of a functional receptor-effector system for VD sub(3) and multiple biological responses to the hormone, these cells provide a unique model system with which to probe the specific effects of VD sub(3) on cell growth and differentiation in chronic myelogenous leukemia.</abstract></addata></record>
fulltext fulltext
identifier ISSN: 0008-5472
ispartof Cancer research (Chicago, Ill.), 1990-01, Vol.50 (10), p.3087-3094
issn 0008-5472
language eng
recordid cdi_proquest_miscellaneous_15794170
source American Association for Cancer Research; EZB-FREE-00999 freely available EZB journals
subjects chronic myeloid leukemia
title Effects of 1 alpha ,25-dihydroxyvitamin D sub(3) on the human chronic myelogenous leukemia cell line RWLeu-4
url https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-03T04%3A06%3A09IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Effects%20of%201%20alpha%20,25-dihydroxyvitamin%20D%20sub(3)%20on%20the%20human%20chronic%20myelogenous%20leukemia%20cell%20line%20RWLeu-4&rft.jtitle=Cancer%20research%20(Chicago,%20Ill.)&rft.au=Lasky,%20SR&rft.date=1990-01-01&rft.volume=50&rft.issue=10&rft.spage=3087&rft.epage=3094&rft.pages=3087-3094&rft.issn=0008-5472&rft_id=info:doi/&rft_dat=%3Cproquest%3E15794170%3C/proquest%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=15794170&rft_id=info:pmid/&rfr_iscdi=true