Influence of perinatal ochratoxin A exposure on the immune system in mice

The mycotoxin ochratoxin A (OA) is a well-documented immunotoxic agent which affects both cellular and humoral immunity. In the present study, the effects of maternal exposure to single doses of OA during gestation or lactation were studied in Balb/c offspring. A single dose exposure of the dams to...

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Veröffentlicht in:	Natural toxins 1996, Vol.4 (4), p.174-180
Hauptverfasser:	Thuvander, A. (Swedish National Food Administration, Uppsala, Sweden.), Dahl, P, Breitholtz-Emanuelsson, A
Format:	Artikel
Sprache:	eng
Schlagworte:	Administration, Oral Analysis of Variance Animals Animals, Suckling Antibody Formation - drug effects Antibody Formation - immunology Antibody response Aspergillus Body Weight - drug effects Carcinogens - toxicity CD4-CD8 Ratio - drug effects CD4-Positive T-Lymphocytes - drug effects CD4-Positive T-Lymphocytes - immunology CD8-Positive T-Lymphocytes - drug effects CD8-Positive T-Lymphocytes - immunology Cell Division - drug effects Cells, Cultured Female Fluorescein-5-isothiocyanate - chemistry Immunotoxicity Kidney - drug effects Kidney - metabolism Lactational transfer Lymphocyte blastogenesis Male Mice Mice, Inbred BALB C Mycotoxins - toxicity OCHRATOXINE Ochratoxins - administration & dosage Ochratoxins - toxicity OCRATOXINA Organ Size - drug effects Penicillium Placental transfer Pregnancy Prenatal Exposure Delayed Effects Spleen - cytology Spleen - drug effects T-Lymphocytes - cytology T-Lymphocytes - drug effects T-Lymphocytes - immunology Thymus Gland - cytology Thymus Gland - drug effects
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