Early B‐Cell Factor (EBF) Down‐Regulates Immunoglobulin Heavy Chain Intron Enhancer Function in a Plasmacytoma Cell Line

The immunoglobulin heavy chain intron enhancer contains two potential binding sites for early B‐cell factor (EBF). To investigate the functional properties of these, EBF was expressed in the EBF non‐expressing S194 plasmacytoma cell line and found to down‐regulate the activity of a co‐transfected im...

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Veröffentlicht in:	Scandinavian journal of immunology 1996-07, Vol.44 (1), p.89-92
Hauptverfasser:	ÅKERBLAD, P., SIGVARDSSON, M., LEANDERSON, T.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Base Sequence DNA-Binding Proteins - pharmacology Enhancer Elements, Genetic - immunology Genes, Immunoglobulin - drug effects Genes, Immunoglobulin - immunology Immunoglobulin Heavy Chains - drug effects Immunoglobulin Heavy Chains - genetics Introns - drug effects Introns - immunology Mice Molecular Sequence Data Plasmacytoma - genetics Plasmacytoma - immunology Trans-Activators - pharmacology Tumor Cells, Cultured
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