Aminoacylation identity switch of turnip yellow mosaic virus RNA from valine to methionine results in an infectious virus

The turnip yellow mosaic virus genomic RNA terminates at its 3' end in a tRNA-like structure that is capable of specific valylation. By directed mutation, the aminoacylation specificity has been switched from valine to methionine, a novel specificity for viral tRNA-like structures. The switch t...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Proceedings of the National Academy of Sciences - PNAS 1996-10, Vol.93 (22), p.12212-12216
Hauptverfasser:	Dreher, T.W. (National Chung Hsing University, Taichung, Taiwan.), Tsai, C.H, Skuzeski, J.M
Format:	Artikel
Sprache:	eng
Schlagworte:	Anticodon ARN ARN DE TRANSFERENCIA ARN DE TRANSFERT Biochemistry BRASSICA CAMPESTRIS BRASSICA CHINENSIS Genes Genetic mutation GENOMAS GENOME Genomes Genomics Kinetics LIGASAS LIGASE METHIONINE Methionine-tRNA Ligase - metabolism METIONINA MUTACION MUTACION INDUCIDA Mutagenesis, Site-Directed MUTATION MUTATION PROVOQUEE Nucleic Acid Conformation Nucleotides PATOGENICIDAD POUVOIR PATHOGENE Protoplasts REACCIONES QUIMICAS REACTION CHIMIQUE Ribonucleic acid RNA RNA, Transfer, Amino Acyl - chemistry RNA, Viral - chemistry Structure-Activity Relationship Transfer RNA turnip yellow mosaic virus TYMOVIRUS Tymovirus - genetics Tymovirus - pathogenicity VALINA VALINE Virion - chemistry Virions VIRUS DE LAS PLANTAS VIRUS DES VEGETAUX Viruses
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!