Mutational analysis of the human HSP70 protein: Distinct domains for nucleolar localization and adenosine triphosphate binding

The human HSP70 gene was modified in vitro using oligonucleotide-directed mutagenesis to add sequences encoding a peptide from the testis-specific form of human lactate dehydrogenase (LDH) to the carboxy terminus of HSP70. A series of deletion mutants within the HSP70 protein coding region were gene...

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Veröffentlicht in:	Cell 1989-01, Vol.109 (5), p.1947-1962
Hauptverfasser:	Milarski, K L, Morimoto, R I
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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