Comparative teratological studies on TCDD, endrin and lindane in C57BL/6J and DBA/2J mice

The teratogenic effects of endrin and lindane have been determined and compared to those induced by TCDD in the fetuses of C57BL/6J and DBA/2J mice after the administration of single oral doses to pregnant mice on day 12 of gestation. TCDD produced dose-dependent decreases in fetal weight, fetal thy...

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Veröffentlicht in:	Comparative biochemistry and physiology. C, Comparative pharmacology and toxicology Comparative pharmacology and toxicology, 1996-03, Vol.113 (3), p.393-398
Hauptverfasser:	Hassoun, E.A., Stohs, S.J.
Format:	Artikel
Sprache:	eng
Schlagworte:	Abnormalities, Drug-Induced Animals C57BL/6J mice Cleft Palate - chemically induced DBA/2J mice Dose-Response Relationship, Drug endrin Endrin - administration & dosage Endrin - toxicity Female fetotoxicity Gestational Age Hydronephrosis - chemically induced Insecticides - toxicity lindane Lindane - administration & dosage Lindane - toxicity Mice Mice, Inbred C57BL Mice, Inbred DBA Polychlorinated Dibenzodioxins - administration & dosage Polychlorinated Dibenzodioxins - toxicity Pregnancy TCDD teratology
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