Methods for assessing sperm motility, morphology, and counts in the rat, rabbit, and dog: A consensus report
Reproductive toxicity studies are increasingly including assessments of sperm parameters including motility, morphology, and counts. While these assessments can provide valuable information for the determination of potential reproductive toxicity, the methods for conducting the assessments have not...
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| Veröffentlicht in: | Reproductive toxicology (Elmsford, N.Y.) N.Y.), 1996-05, Vol.10 (3), p.237-244 |
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| container_title | Reproductive toxicology (Elmsford, N.Y.) |
| container_volume | 10 |
| creator | Seed, Jennifer Chapin, Robert E. Clegg, Eric D. Dostal, Lori A. Foote, Robert H. Hurtt, Mark E. Klinefelter, Gary R. Makris, Susan L. Perreault, Sally D. Schrader, Steve Seyler, David Sprando, Robert Treinen, Kimberley A. Veeramachaneni, D.N.Rao Wise, L.David |
| description | Reproductive toxicity studies are increasingly including assessments of sperm parameters including motility, morphology, and counts. While these assessments can provide valuable information for the determination of potential reproductive toxicity, the methods for conducting the assessments have not been well developed in all laboratories and are continually evolving. The use of different methods in different laboratories makes comparison of data among laboratories difficult. To address the differences in methods, a working group was convened to discuss methods currently in use, share data, and try to reach consensus about optimal methods for assessing sperm parameters in rats, rabbits, and dogs. This article presents the consensus report, as well as future research needs, with the hope that optimized common methods will aid in the detection of reproductive effects and enhance interlaboratory comparisons. |
| doi_str_mv | 10.1016/0890-6238(96)00028-7 |
| format | Article |
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While these assessments can provide valuable information for the determination of potential reproductive toxicity, the methods for conducting the assessments have not been well developed in all laboratories and are continually evolving. The use of different methods in different laboratories makes comparison of data among laboratories difficult. To address the differences in methods, a working group was convened to discuss methods currently in use, share data, and try to reach consensus about optimal methods for assessing sperm parameters in rats, rabbits, and dogs. This article presents the consensus report, as well as future research needs, with the hope that optimized common methods will aid in the detection of reproductive effects and enhance interlaboratory comparisons.</description><subject>Biological and medical sciences</subject><subject>dog</subject><subject>Fundamental and applied biological sciences. Psychology</subject><subject>General aspects. Methods</subject><subject>Mammalian male genital system</subject><subject>Medical sciences</subject><subject>methods</subject><subject>Morphology. 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| identifier | ISSN: 0890-6238 |
| ispartof | Reproductive toxicology (Elmsford, N.Y.), 1996-05, Vol.10 (3), p.237-244 |
| issn | 0890-6238 1873-1708 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_15755358 |
| source | Elsevier ScienceDirect Journals |
| subjects | Biological and medical sciences dog Fundamental and applied biological sciences. Psychology General aspects. Methods Mammalian male genital system Medical sciences methods Morphology. Physiology rabbit rat sperm counts sperm morphology sperm motility Toxicology Vertebrates: reproduction |
| title | Methods for assessing sperm motility, morphology, and counts in the rat, rabbit, and dog: A consensus report |
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