A Facile and Practical Synthesis of 9-Methyl-3-(1H-tetrazol-5-yl)-4H-pyrido[1, 2-α]pyrimidin-4-one

A facile and practical synthesis of 9-methyl-3-(1H-tetrazol-5-yl)-4H-pyrido[1, 2-α]pyrimidin-4-one (4), the potassium salt of which is used clinically as an anti-asthma agent, is described. Treatment of a key intermediate (6b), prepared from 2-amino-3-methylpyridine (1) and 2-ethoxymethylene-1, 3-pr...

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Veröffentlicht in:	Chemical & pharmaceutical bulletin 1995/04/15, Vol.43(4), pp.683-685
Hauptverfasser:	SANO, Atsunori, ISHIHARA, Masami, YOSHIHARA, Jun, SUMINO, Motoshige, NAWA, Hiromi
Format:	Artikel
Sprache:	eng
Schlagworte:	1H-tetrazole 4H-pyrido[1, 2-α]pyrimidine alternative synthesis anti-asthma agent Chemistry Exact sciences and technology Heterocyclic compounds Heterocyclic compounds with several n hetero atoms in the same ring, in separated rings or in fused rings one-pot synthesis Organic chemistry Preparations and properties sodium azide
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