Metal-stabilized rare tautomers of nucleobases. 2. 2-Oxo-4-hydroxo form of uracil: crystal structures and solution behavior of two platinum(II) complexes containing iminol tautomers of 1-methyluracil
A model for a metal-assisted tautomerization of the pyrimidine model nucleobase 1-methyluracil is presented which, by analogy, could account for mutagenic AT arrow right GC or GC arrow right AT transition in DNA. It involves initial metal binding to the N3 site of a thymine anion, followed by proton...
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| Veröffentlicht in: | Journal of the American Chemical Society 1989-08, Vol.111 (18), p.7213-7221 |
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| Hauptverfasser: | , , |
| Format: | Artikel |
| Sprache: | eng |
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