Hepatotoxicity of N, N-dimethylformamide in rats following intraperitoneal or inhalation routes of administration

Male Sprague-Dawley rats were administered a single intraperitoneal injection of N, N-dimethylformamide (DMF, 0.01-1.5 g kg-1) or were exposed for 4 h to DMF vapours (75-900 ppm). The serum activities of the enzymes sorbitol deshydrogenase and glutamate deshydrogenase were used as indicators of live...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Journal of applied toxicology 1996-05, Vol.16 (3), p.265-267
Hauptverfasser:	ROURE, M. B, LAMBERT, A. M, COUR, C, BONNET, P, SAILLENFAIT, A. M
Format:	Artikel
Sprache:	eng
Schlagworte:	Administration, Inhalation Animals Biological and medical sciences Chemical and industrial products toxicology. Toxic occupational diseases Dimethylformamide - administration & dosage Dimethylformamide - toxicity Glutamate Dehydrogenase - analysis Injections, Intraperitoneal L-Iditol 2-Dehydrogenase - analysis Liver - drug effects Liver - enzymology Male Medical sciences Rats Rats, Sprague-Dawley Solvents Toxicity Tests Toxicology
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!