Development of cholinergic markers in the neuroblastoma, N1E-115

The neuroblastoma, N1E‐115, was grown for 9 days after subcultivation. The development of acetylcholinestrase (AChE), choline acetyltransferase (CAT), QNB‐binding, choline uptake, and acetylcholine release was measured on days 1, 3, 6, and 9. In paralell experiments the irreversible AChE inhibitor s...

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Veröffentlicht in:	Journal of neuroscience research 1990-09, Vol.27 (1), p.99-105
Hauptverfasser:	Kumar, U., Sellström, Å.
Format:	Artikel
Sprache:	eng
Schlagworte:	acetylcholine Acetylcholine - secretion Acetylcholinesterase - analysis AChE Animals Biological and medical sciences Biomarkers CAT Cell Division - drug effects Cell physiology choline Choline - metabolism Choline O-Acetyltransferase - analysis Down-Regulation - drug effects Fundamental and applied biological sciences. Psychology Mice Molecular and cellular biology muscarinic receptor muscarinic receptor choline Neuroblastoma - pathology Neurotransmission Quinuclidinyl Benzilate - metabolism Receptors, Muscarinic - metabolism release of release of soman soman Soman - metabolism Soman - pharmacology transport of transport of acetylcholine Tumor Cells, Cultured - chemistry Tumor Cells, Cultured - drug effects
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