Isolation and structure of the cytostatic depsipeptide dolastatin 13 from the sea hare Dolabella auricularia
The Indian Ocean shell-less mollusc Dolabella auricularia superficially appears to lack predator defenses. Such seemingly defenseless animals are only attacked by certain carnivorous members of this gastropod subclass. Evidence is now accumulating that Opisthobranchia species have developed very pow...
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Veröffentlicht in: | Journal of the American Chemical Society 1989, Vol.111 (13), p.5015-5017 |
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container_title | Journal of the American Chemical Society |
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creator | PETTIT, G. R KAMANO, Y HERALD, C. L DUFRESNE, C CERNY, R. L HERALD, D. L SCHMIDT, J. M KIZU, H |
description | The Indian Ocean shell-less mollusc Dolabella auricularia superficially appears to lack predator defenses. Such seemingly defenseless animals are only attacked by certain carnivorous members of this gastropod subclass. Evidence is now accumulating that Opisthobranchia species have developed very powerful chemical defenses by careful selection and/or biosynthetic manipulation of various dietary sources such as blue-green algae and sponges. |
doi_str_mv | 10.1021/ja00195a084 |
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R ; KAMANO, Y ; HERALD, C. L ; DUFRESNE, C ; CERNY, R. L ; HERALD, D. L ; SCHMIDT, J. M ; KIZU, H</creator><creatorcontrib>PETTIT, G. R ; KAMANO, Y ; HERALD, C. L ; DUFRESNE, C ; CERNY, R. L ; HERALD, D. L ; SCHMIDT, J. M ; KIZU, H</creatorcontrib><description>The Indian Ocean shell-less mollusc Dolabella auricularia superficially appears to lack predator defenses. Such seemingly defenseless animals are only attacked by certain carnivorous members of this gastropod subclass. 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M</creatorcontrib><creatorcontrib>KIZU, H</creatorcontrib><title>Isolation and structure of the cytostatic depsipeptide dolastatin 13 from the sea hare Dolabella auricularia</title><title>Journal of the American Chemical Society</title><description>The Indian Ocean shell-less mollusc Dolabella auricularia superficially appears to lack predator defenses. Such seemingly defenseless animals are only attacked by certain carnivorous members of this gastropod subclass. Evidence is now accumulating that Opisthobranchia species have developed very powerful chemical defenses by careful selection and/or biosynthetic manipulation of various dietary sources such as blue-green algae and sponges.</description><subject>Analytical, structural and metabolic biochemistry</subject><subject>Biological and medical sciences</subject><subject>Carbohydrates</subject><subject>Dolabella auricularia</subject><subject>Fundamental and applied biological sciences. 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Psychology</topic><topic>Marine</topic><topic>Other biological molecules</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>PETTIT, G. R</creatorcontrib><creatorcontrib>KAMANO, Y</creatorcontrib><creatorcontrib>HERALD, C. L</creatorcontrib><creatorcontrib>DUFRESNE, C</creatorcontrib><creatorcontrib>CERNY, R. L</creatorcontrib><creatorcontrib>HERALD, D. L</creatorcontrib><creatorcontrib>SCHMIDT, J. M</creatorcontrib><creatorcontrib>KIZU, H</creatorcontrib><collection>Pascal-Francis</collection><collection>ASFA: Aquatic Sciences and Fisheries Abstracts</collection><collection>Aquatic Science & Fisheries Abstracts (ASFA) 1: Biological Sciences & Living Resources</collection><collection>Aquatic Science & Fisheries Abstracts (ASFA) Professional</collection><jtitle>Journal of the American Chemical Society</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>PETTIT, G. R</au><au>KAMANO, Y</au><au>HERALD, C. L</au><au>DUFRESNE, C</au><au>CERNY, R. L</au><au>HERALD, D. L</au><au>SCHMIDT, J. M</au><au>KIZU, H</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Isolation and structure of the cytostatic depsipeptide dolastatin 13 from the sea hare Dolabella auricularia</atitle><jtitle>Journal of the American Chemical Society</jtitle><date>1989</date><risdate>1989</risdate><volume>111</volume><issue>13</issue><spage>5015</spage><epage>5017</epage><pages>5015-5017</pages><issn>0002-7863</issn><eissn>1520-5126</eissn><coden>JACSAT</coden><abstract>The Indian Ocean shell-less mollusc Dolabella auricularia superficially appears to lack predator defenses. Such seemingly defenseless animals are only attacked by certain carnivorous members of this gastropod subclass. Evidence is now accumulating that Opisthobranchia species have developed very powerful chemical defenses by careful selection and/or biosynthetic manipulation of various dietary sources such as blue-green algae and sponges.</abstract><cop>Washington, DC</cop><pub>American Chemical Society</pub><doi>10.1021/ja00195a084</doi><tpages>3</tpages></addata></record> |
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source | ACS Publications |
subjects | Analytical, structural and metabolic biochemistry Biological and medical sciences Carbohydrates Dolabella auricularia Fundamental and applied biological sciences. Psychology Marine Other biological molecules |
title | Isolation and structure of the cytostatic depsipeptide dolastatin 13 from the sea hare Dolabella auricularia |
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