Platelet-activating factor and endotoxin increase the enzyme activity and gene expression of type II phospholipase a sub(2) in the rat intestine. Role of polymorphonuclear leukocytes

Type II phospholipase A sub(2) (PLA sub(2)-II) may regulate eicosanoid synthesis; is involved in various inflammatory processes, septic shock, and inflammatory bowel disease; and is up-regulated by LPS and inflammatory cytokines in vitro. We have previously shown that the platelet-activating factor...

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Veröffentlicht in:The Journal of immunology (1950) 1996-01, Vol.156 (8), p.2985-2990
Hauptverfasser: Tan, Xiao-Di, Wang, Hao, Gonzalez-Crussi, F X, Chang, Hong, Gonzalez-Crussi, F, Hsueh, Wei
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Sprache:eng
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