Secretagogues Increase the Expression of Surfactant Protein A Receptors on Lung Type II Cells

Since secretagogues have been shown to increase the internalization of surfactant phospholipid and protein by lung cells, we postulated that their action occurred through a mechanism involving increased surfactant protein A (SP-A) receptor density. Therefore, we evaluated the influence of secretagog...

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Veröffentlicht in:	The Journal of biological chemistry 1996-10, Vol.271 (41), p.25277-25283
Hauptverfasser:	Chen, Qiping, Bates, Sandra R., Fisher, Aron B.
Format:	Artikel
Sprache:	eng
Schlagworte:	8-Bromo Cyclic Adenosine Monophosphate - pharmacology Adenosine Triphosphate - pharmacology Animals Calcium - metabolism Cells, Cultured Cyclic AMP - physiology Cycloheximide - pharmacology Drug Interactions Glycoproteins - metabolism Kinetics Lung - cytology Lung - drug effects Lung - metabolism Male Membranes, Artificial Proteolipids - metabolism Pulmonary Surfactant-Associated Protein A Pulmonary Surfactant-Associated Proteins Pulmonary Surfactants - metabolism Rats Rats, Sprague-Dawley Receptors, Cell Surface - biosynthesis Terbutaline - pharmacology Tetradecanoylphorbol Acetate - pharmacology Trypsin - pharmacology Up-Regulation - drug effects
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