Photochemical approach to the synthesis of the pyrrolo[1,4]benzodiazepine antibiotics

The total syntheses of the pyrrolo (1,4)benzodiazepine antitumor antibiotics prothracarcin and DC-81 were realized using, as a key step, the photochemical (2 sigma + 2 pi ) ring expansion of the appropriately substituted N-pentenylphthalimide to afford the corresponding pyrrolobenzazepinedione. Conv...

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Veröffentlicht in:	Journal of organic chemistry 1989-11, Vol.54 (24), p.5746-5758
Hauptverfasser:	Weidner-Wells, Michele A, DeCamp, Ann, Mazzocchi, Paul H
Format:	Artikel
Sprache:	eng
Schlagworte:	Chemistry Exact sciences and technology Heterocyclic compounds Heterocyclic compounds with only one n hetero atom and condensed derivatives Organic chemistry Preparations and properties
Online-Zugang:	Volltext
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