Cytotoxic and chemotactic potencies of several aldehydic components of oxidised low density lipoprotein for human monocyte-macrophages

We have investigated the cytotoxic and chemotactic potencies of malondialdehyde (MDA), hexanal, 4-hydroxyhexenal (HHE), 4-hydroxynonenal (HNE) and 4-hydroxyoctenal (HOE), which are aldehydes found in oxidised low density lipoprotein (LDL), for human monocyte-macrophages. They were toxic in the follo...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	FEBS letters 1996-06, Vol.388 (2), p.165-168
Hauptverfasser:	Müller, Karin, Hardwick, Simon J., Marchant, Christine E., Law, Nadine S., Waeg, Georg, Esterbauer, Hermann, Carpenter, Keri L.H., Mitchinson, Malcolm J.
Format:	Artikel
Sprache:	eng
Schlagworte:	Aldehydes Aldehydes - metabolism Aldehydes - pharmacology Atherosclerosis Chemotactic Factors - metabolism Chemotactic Factors - physiology Chemotaxis Cytotoxicity Cytotoxins - metabolism Cytotoxins - physiology Humans Lipoproteins, LDL - metabolism Lipoproteins, LDL - physiology Macrophages - metabolism Malondialdehyde - metabolism Monocyte-macrophage (human) Monocytes - metabolism Oxidation-Reduction Oxidised LDL
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!