The Effect of 4-Substituent of Benzoic Acid on Glycine Conjugation

The relationship between the glycine conjugation of 4-substituted derivatives of benzoic acid and physico-chemical property was studied using rats. A linear relationship was found between the lipophilicity and the glycine conjugation after the intravenous injection of the derivative into rats. But t...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Chemical & pharmaceutical bulletin 1990/06/25, Vol.38(6), pp.1753-1754
Hauptverfasser:	NANBO, Toshio, FUKASAKU, Noboru, YAMAGUCHI, Michio, TAKAGI, Hideyuki, UEDA, Takao, YOKOSHIMA, Tetsuyoshi
Format:	Artikel
Sprache:	eng
Schlagworte:	4-substitution benzoic acid Biological and medical sciences glycine conjugation Medical sciences Miscellaneous partition coefficient permeability superdelocalizability Toxicology
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!