Compensations after lesions of central dopaminergic neurons: some clinical and basic implications

Parkinson's disease is associated with degeneration of the dopaminergic component of the nigrostriatal pathway. However, the neurological symptoms of this disorder do not emerge until the degenerative process is almost complete. A comparable phenomenon can be observed in animal models of Parkin...

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Veröffentlicht in:	Trends in Neurosciences 1990-07, Vol.13 (7), p.290-296
Hauptverfasser:	Zigmond, Michael J., Abercrombie, Elizabeth D., Berger, Theodore W., Grace, Anthony A., Stricker, Edward M.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adaptation, Physiological Animals Brain - physiology Brain Diseases - pathology Brain Diseases - physiopathology Disease Models, Animal Dopamine - physiology Humans Neurons - pathology Neurons - physiology Parkinson Disease - physiopathology
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