Double modulation of 5-fluorouracil in advanced colorectal cancer with low-dose interferon- alpha 2b and folinic acid. The "GISCAD" experience
In advanced colorectal cancer the addition of folinic acid (FA) has been shown to lead to increased activity, at least in terms of response rate, in comparison with 5-fluorouracil (5FU) alone. Similarly, interferon- alpha (IFN) is able to potentiate 5FU, although high doses cause heavy toxicity. Giv...
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Veröffentlicht in: | European journal of cancer (1990) 1994-01, Vol.30A (11), p.1611-1620 |
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Format: | Artikel |
Sprache: | eng |
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