The tumor suppressor gene, lethal(2)giant larvae (l(2)gl) , is required for cell shape change of epithelial cells during Drosophila development

Inactivation of the lethal(2)giant larvae (l(2)gl) gene results in malignant transformation of imaginal disc cells and neuroblasts of the larval brain in Drosophila. Subcellular localization of the l(2)gl gene product, P127, and its biochemical characterization have indicated that it participates in...

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Veröffentlicht in:	Development (Cambridge) 1996-07, Vol.122 (7), p.2283-2294
Hauptverfasser:	Manfruelli, P., Arquier, N., Hanratty, W. P., Sémériva, M.
Format:	Artikel
Sprache:	eng
Schlagworte:	Diptera Drosophila Drosophilidae
Online-Zugang:	Volltext
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