Inhibition of translational initiation by activators of the glucose-regulated stress protein and heat shock protein stress response systems: Role of the interferon-inducible double-stranded RNA-activated eukaryotic initiation factor 2 alpha kinase

Depletion of endoplasmic reticulum (ER) Ca super(2+) perturbs protein folding and processing within the organelle while inhibiting translational initiation through activation of the double-stranded RNA-activated eukaryotic initiation factor (eIF)-2 alpha kinase (PKR). The glucose-regulated stress pr...

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Veröffentlicht in:	The Journal of biological chemistry 1996, Vol.271 (40), p.24995-25002
Hauptverfasser:	Brostrom, C O, Prostko, C R, Kaufman, R J, Brostrom, MA
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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