Influence of resveratrol on rheumatoid fibroblast-like synoviocytes analysed with gene chip transcription

Rheumatoid arthritis (RA) is a chronic, systemic autoimmune disease that primarily attacks joints and is therefore a common cause of chronic disability and articular destruction. The hyperplastic growth of RA-fibroblast-like synoviocytes (FLSs) and their resistance against apoptosis are considered p...

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Veröffentlicht in:	Phytomedicine (Stuttgart) 2013-02, Vol.20 (3-4), p.310-318
Hauptverfasser:	Glehr, Mathias, Fritsch-Breisach, Margherita, Lohberger, Birgit, Walzer, Sonja Maria, Moazedi-Fuerst, Florentine, Rinner, Beate, Gruber, Gerald, Graninger, Winfried, Leithner, Andreas, Windhager, Reinhard
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Analysis Anti-Inflammatory Agents - therapeutic use Antioxidants Antioxidants - pharmacology Antioxidants - therapeutic use Apoptosis Apoptosis - drug effects Arthritis, Rheumatoid - drug therapy Arthritis, Rheumatoid - genetics Arthritis, Rheumatoid - metabolism Biotechnology industry Caspase 3 - metabolism Caspase 7 - metabolism Cell Movement - drug effects Cell Proliferation - drug effects Cells, Cultured Dexamethasone - therapeutic use DNA microarrays Drug Evaluation, Preclinical Female Fibroblast-like synoviocytes Gene chip transcription analysis Gene Expression Profiling Genetic aspects Genetic transcription Humans Male Middle Aged Oligonucleotide Array Sequence Analysis Phenotype Phytotherapy Proliferation Real-Time Polymerase Chain Reaction Resveratrol Rheumatoid arthritis Rheumatoid factor Stilbenes - pharmacology Stilbenes - therapeutic use
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