Quantifying Mitotic Chromosome Dynamics and Positioning
The proper organization and segregation of chromosomes during cell division is essential to the preservation of genomic integrity. To understand the mechanisms that spatially control the arrangement and dynamics of mitotic chromosomes requires imaging assays to quantitatively resolve their positions...
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Veröffentlicht in: | Journal of cellular physiology 2014-10, Vol.229 (10), p.1301-1305 |
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description | The proper organization and segregation of chromosomes during cell division is essential to the preservation of genomic integrity. To understand the mechanisms that spatially control the arrangement and dynamics of mitotic chromosomes requires imaging assays to quantitatively resolve their positions and movements. Here, we will discuss analytical approaches to investigate the position‐dependent control of mitotic chromosomes in cultured cells. These methods can be used to dissect the specific contributions of mitotic proteins to the molecular control of chromosome dynamics. J. Cell. Physiol. 229: 1301–1305, 2014. © 2014 Wiley Periodicals, Inc. |
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Physiol. 229: 1301–1305, 2014. © 2014 Wiley Periodicals, Inc.</description><subject>Animals</subject><subject>Cell Cycle Proteins - metabolism</subject><subject>Cells, Cultured</subject><subject>Chromosome Segregation</subject><subject>Chromosomes</subject><subject>Chromosomes - metabolism</subject><subject>Chromosomes - ultrastructure</subject><subject>Humans</subject><subject>Kinetics</subject><subject>Kinetochores - metabolism</subject><subject>Mitosis</subject><subject>Molecular Imaging - methods</subject><issn>0021-9541</issn><issn>1097-4652</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2014</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqN0E1P2zAYB3BrGlpLt8O-wBSJyzgEHr_EL0fU0QJqWSdt6tFyHWe4NHGJE0G_PR4FDkhIk2z54N_zt_xH6CuGEwxATtd2e0IYp-wDGmJQIme8IB_RMN3hXBUMD9BhjGsAUIrST2iQsKQg8RCJX71pOl_tfPM3m_sudN5m45s21CGG2mU_do2pvY2ZacpsEaLvfGiS_YwOKrOJ7svzOUJ_Jue_xxf57Of0cnw2yy1TwHJDBVSlMJgxTKRc2UrItCyV4KqVKiwmBVBbEspp2lhAWSnOVpSUxJaS0xH6vs_dtuGud7HTtY_WbTamcaGPGhecy4ICx_9BGQFgkB4aoaM3dB36tkkfSaqgmHElaFLHe2XbEGPrKr1tfW3ancag_xWvU_H6qfhkvz0n9qvala_ypekETvfg3m_c7v0kfTVevETm-wkfO_fwOmHaW80FFYVeXk_1bCKkWsyXek4fARObmMU</recordid><startdate>201410</startdate><enddate>201410</enddate><creator>Bissonette, Samantha</creator><creator>Stumpff, Jason</creator><general>Blackwell Publishing Ltd</general><general>Wiley Subscription Services, Inc</general><scope>BSCLL</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7TK</scope><scope>7U7</scope><scope>8FD</scope><scope>C1K</scope><scope>FR3</scope><scope>K9.</scope><scope>P64</scope><scope>RC3</scope><scope>7X8</scope></search><sort><creationdate>201410</creationdate><title>Quantifying Mitotic Chromosome Dynamics and Positioning</title><author>Bissonette, Samantha ; Stumpff, Jason</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c4904-a370fd7a1441288bcf78f78c380efb95c12503cd2363236170df964b32d2cd863</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2014</creationdate><topic>Animals</topic><topic>Cell Cycle Proteins - metabolism</topic><topic>Cells, Cultured</topic><topic>Chromosome Segregation</topic><topic>Chromosomes</topic><topic>Chromosomes - metabolism</topic><topic>Chromosomes - ultrastructure</topic><topic>Humans</topic><topic>Kinetics</topic><topic>Kinetochores - metabolism</topic><topic>Mitosis</topic><topic>Molecular Imaging - methods</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Bissonette, Samantha</creatorcontrib><creatorcontrib>Stumpff, Jason</creatorcontrib><collection>Istex</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Neurosciences Abstracts</collection><collection>Toxicology Abstracts</collection><collection>Technology Research Database</collection><collection>Environmental Sciences and Pollution Management</collection><collection>Engineering Research Database</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>Genetics Abstracts</collection><collection>MEDLINE - Academic</collection><jtitle>Journal of cellular physiology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Bissonette, Samantha</au><au>Stumpff, Jason</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Quantifying Mitotic Chromosome Dynamics and Positioning</atitle><jtitle>Journal of cellular physiology</jtitle><addtitle>J. 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subjects | Animals Cell Cycle Proteins - metabolism Cells, Cultured Chromosome Segregation Chromosomes Chromosomes - metabolism Chromosomes - ultrastructure Humans Kinetics Kinetochores - metabolism Mitosis Molecular Imaging - methods |
title | Quantifying Mitotic Chromosome Dynamics and Positioning |
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