Packaging, Amplification, and Appraisal of the Recombinant Tumor-Selective Type I Herpes Simplex Virus Carrying GALV.fus Gene

The aim of the study was to successfully construct three plasmids, which include the GALV.fus gene plasmid regulated by the herpes simplex virus type 1 (HSV-1) late expression gene-UL38 promoter and induced by HSV-1 (HSV-UL38P-GALV.fus), the cytomegalovirus promoter without tumor specificity (CMVP)...

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Veröffentlicht in:	Cell biochemistry and biophysics 2014-09, Vol.70 (1), p.321-326
Hauptverfasser:	Bing, Zhu, Jianru, Yang, Yuequan, Jiang, Shifeng, Chen, Xinping, Fu
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biochemistry Biological and Medical Physics Biomedical and Life Sciences Biophysics Biotechnology Cell Biology Centrifugation Cercopithecus aethiops Cesium Cytomegalovirus DNA, Recombinant - genetics Genetic Engineering - methods Genetic Therapy Hep G2 Cells Herpes simplex virus 1 Herpesvirus 1, Human - genetics Herpesvirus 1, Human - physiology Humans Leukemia Virus, Gibbon Ape - genetics Life Sciences Lung Neoplasms - genetics Lung Neoplasms - therapy Nucleic Acid Amplification Techniques Original Paper Pharmacology/Toxicology Plasmids - genetics RNA - genetics RNA - isolation & purification RNA-Binding Protein FUS - genetics Transfection Vero Cells Virus Assembly
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