The Human Antiviral Factor TRIM11 Is under the Regulation of HIV-1 Vpr: e104269

TRIM11 has been reported to be able to restrict HIV-1 replication, but the detailed aspects of the interfering mechanisms remain unclear. In this study, we demonstrated that TRIM11 mainly suppressed the early steps of HIV-1 transduction, resulting in decreased reverse transcripts. Additionally, we f...

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Veröffentlicht in:PloS one 2014-08, Vol.9 (8)
Hauptverfasser: Yuan, Ting, Yao, Weitong, Huang, Fang, Sun, Binlian, Yang, Rongge
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Sprache:eng
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