Serum cytokine/chemokine profiles in acute exacerbation of chronic hepatitis B: Clinical and mechanistic implications

Background and Aims Acute exacerbation (AE) of chronic hepatitis B virus (HBV) infection is common and negatively impacts the clinical outcome. Although upsurge of viral load always precedes or coincides with AE, the underlying immunological mechanisms remain unclear and were investigated. Methods W...

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Veröffentlicht in:	Journal of gastroenterology and hepatology 2014-08, Vol.29 (8), p.1629-1636
Hauptverfasser:	Wu, Hui-Lin, Kao, Jia-Horng, Chen, Ting-Chih, Wu, Wen-Hsuan, Liu, Chen-Hua, Su, Tung-Hung, Yang, Hung-Chih, Chen, Ding-Shinn, Chen, Pei-Jer, Liu, Chun-Jen
Format:	Artikel
Sprache:	eng
Schlagworte:	acute exacerbation Adult Alanine Transaminase - blood Biomarkers - blood chemokine Chemokine CXCL10 - blood Chemokines - blood cytokine Cytokines - blood Disease Progression DNA, Viral - blood Female Follow-Up Studies hepatitis B Hepatitis B virus Hepatitis B virus - genetics Hepatitis B, Chronic - blood Hepatitis B, Chronic - virology Humans Interleukin-10 - blood Interleukin-4 - blood Interleukin-6 - blood Male Middle Aged Viral Load
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