Non-small cell lung cancer patients with EML4-ALK fusion gene are insensitive to cytotoxic chemotherapy

Although patients with the echinoderm microtubule-associated protein-like 4-anaplastic lymphoma kinase gene (EML4-ALK) re-arrangement and epidermal growth factor gene EGFR mutations have proven sensitive to specific inhibitors, there is currently no consensus regarding the sensitivity of non-small c...

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Veröffentlicht in:	Anticancer research 2014-07, Vol.34 (7), p.3825-3830
Hauptverfasser:	Morodomi, Yosuke, Takenoyama, Mitsuhiro, Inamasu, Eiko, Toyozawa, Ryo, Kojo, Miyako, Toyokawa, Gouji, Shiraishi, Yoshimasa, Takenaka, Tomoyoshi, Hirai, Fumihiko, Yamaguchi, Masafumi, Taguchi, Kenichi, Seto, Takashi, Sugio, Kenji, Ichinose, Yukito
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Carcinoma, Non-Small-Cell Lung - drug therapy Carcinoma, Non-Small-Cell Lung - genetics Cohort Studies Disease-Free Survival Drug Resistance, Neoplasm - genetics Female Humans Lung Neoplasms - drug therapy Lung Neoplasms - genetics Male Middle Aged Mutation Oncogene Proteins, Fusion - genetics Receptor, Epidermal Growth Factor - genetics Retrospective Studies
Online-Zugang:	Volltext
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