B‐Cell Receptor‐Associated Protein 31 Regulates Human Embryonic Stem Cell Adhesion, Stemness, and Survival via Control of Epithelial Cell Adhesion Molecule

B‐Cell receptor‐associated protein 31 (BAP31) regulates the export of secreted membrane proteins from the endoplasmic reticulum (ER) to the downstream secretory pathway. Previously, we generated a monoclonal antibody 297‐D4 against the surface molecule on undifferentiated human embryonic stem cells...

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Veröffentlicht in:	Stem cells (Dayton, Ohio) Ohio), 2014-10, Vol.32 (10), p.2626-2641
Hauptverfasser:	Kim, Won‐Tae, Seo Choi, Hong, Min Lee, Hyun, Jang, Young‐Joo, Ryu, Chun Jeih
Format:	Artikel
Sprache:	eng
Schlagworte:	Adhesion Amino Acid Sequence Animals Antigens Antigens - metabolism Antigens, Neoplasm - metabolism Apoptosis BAP31 Caspases - metabolism Cell Adhesion Cell adhesion & migration Cell Adhesion Molecules - metabolism Cell cycle Cell Death Cell Differentiation - genetics Cell Line Cell Lineage Cell Proliferation Cell Survival Down-Regulation Embryonic Stem Cells - cytology Embryonic Stem Cells - metabolism EpCAM Epithelial Cell Adhesion Molecule Extracellular Matrix - metabolism G0/G1 arrest G1 Phase Human embryonic stem cells Humans Membrane Proteins - chemistry Membrane Proteins - metabolism Mice Molecular Sequence Data Phosphatidylinositol 3-Kinases - metabolism Pluripotent Stem Cells - cytology Pluripotent Stem Cells - metabolism Protein Transport Proto-Oncogene Proteins c-akt - metabolism Proto-Oncogene Proteins c-bcl-2 - metabolism Resting Phase, Cell Cycle Signal Transduction Stem cells Stemness
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