Anti-rotavirus effects by combination therapy of stevioside and Sophora flavescens extract

Anti-rotaviral activities of Sophora flavescens extract (SFE) and stevioside (SV) from Stevia rebaudiana Bertoni either singly or in various combinations were examined in vitro and in vivo using a porcine rotavirus G5[P7] strain. Combination of SFE and SV inhibited in vitro virus replication more ef...

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Veröffentlicht in:	Research in veterinary science 2014-06, Vol.96 (3), p.567-575
Hauptverfasser:	Alfajaro, Mia Madel, Rho, Mun-Chual, Kim, Hyun-Jeong, Park, Jun-Gyu, Kim, Deok-Song, Hosmillo, Myra, Son, Kyu-Yeol, Lee, Ju-Hwan, Park, Sang-Ik, Kang, Mun-Il, Ryu, Young Bae, Park, Ki Hun, Oh, Hyun-Mee, Lee, Seung Woong, Park, Su-Jin, Lee, Woo Song, Cho, Kyoung-Oh
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Combination therapy Diarrhea - drug therapy Diarrhea - veterinary Diarrhea - virology Diterpenes, Kaurane - pharmacology Diterpenes, Kaurane - therapeutic use Drug Therapy, Combination Enteritis Feces - virology Female Glucosides - pharmacology Glucosides - therapeutic use Histocytochemistry - veterinary Intestine, Small - virology Male Plant Extracts - administration & dosage Plant Extracts - pharmacology Porcine rotavirus Random Allocation Real-Time Polymerase Chain Reaction - veterinary RNA, Viral - chemistry RNA, Viral - genetics Rotavirus Rotavirus - genetics Rotavirus - growth & development Rotavirus Infections - drug therapy Rotavirus Infections - veterinary Rotavirus Infections - virology Sophora Sophora - metabolism Sophora flavescens extract Stevioside Swine Swine Diseases - drug therapy Swine Diseases - virology Synergistic effect
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