Prognostic impact of KMT2E transcript levels on outcome of patients with acute promyelocytic leukaemia treated with all‐trans retinoic acid and anthracycline‐based chemotherapy: an International Consortium on Acute Promyelocytic Leukaemia study

Summary The KMT2E (MLL5) gene encodes a histone methyltransferase implicated in the positive control of genes related to haematopoiesis. Its close relationship with retinoic acid–induced granulopoiesis suggests that the deregulated expression of KMT2E might lead acute promyelocytic leukaemia (APL) b...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	British journal of haematology 2014-08, Vol.166 (4), p.540-549
Hauptverfasser:	Lucena‐Araujo, Antonio R., Kim, Haesook T., Jacomo, Rafael H., Melo, Raul A., Bittencourt, Rosane, Pasquini, Ricardo, Pagnano, Katia, Fagundes, Evandro M., Chauffaille, Maria, Chiattone, Carlos S., Lima, Ana S., Kwaan, Hau C., Gallagher, Robert, Niemeyer, Charlotte M., Schrier, Stanley L., Tallman, Martin S., Grimwade, David, Ganser, Arnold, Berliner, Nancy, Ribeiro, Raul C., Lo‐Coco, Francesco, Löwenberg, Bob, Sanz, Miguel A., Rego, Eduardo M.
Format:	Artikel
Sprache:	eng
Schlagworte:	acute promyelocytic leukaemia Adolescent Adult all‐trans retinoic acid Anthracyclines - administration & dosage Antineoplastic Combined Chemotherapy Protocols - therapeutic use Biological and medical sciences Case-Control Studies developing countries DNA-Binding Proteins - metabolism Female Hematologic and hematopoietic diseases Humans International Consortium on Acute Promyelocytic Leukaemia KMT2E (MLL5) Leukemia, Promyelocytic, Acute - drug therapy Leukemia, Promyelocytic, Acute - metabolism Leukemias. Malignant lymphomas. Malignant reticulosis. Myelofibrosis Male Medical sciences Middle Aged Treatment Outcome Tretinoin - administration & dosage Tumors Young Adult
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!