Safety in a Phase 1 Randomized, Double-Blinded, Placebo-Controlled Trial Evaluating Two Adenovirus HIV Vaccines in Three Different Geographic Regions

Background: Homologous and heterologous prime-boost regimens were compared using two adenovirus vectors (Ad26.EnvA. 01 [Ad26] and Ad35-EnvA [Ad35]) in the USA, East Africa and South Africa. This is the first trial using either vector for an HIV preventive vaccine in Africa. Safety data between these...

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Veröffentlicht in:AIDS research and human retroviruses 2013-11, Vol.29 (11), p.A-148
Hauptverfasser: Karita, E, Mutua, G, Bekker, L, Gray, G, Page-Shipp, L, Baden, L, Bayingana, R, Nyombayire, J, Anzala, O, Nyasani, D, Roux, S, Mangenya, N, Laher, F, Mambe, M, Innes, C, Mngadi, K, Walsh, S, Johnson, J, Dolin, R, Stevens, G, Grunenberg, N, Barouch, D, Fast, P, Laufer, D
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container_end_page 148
container_issue 11
container_start_page A
container_title AIDS research and human retroviruses
container_volume 29
creator Karita, E
Mutua, G
Bekker, L
Gray, G
Page-Shipp, L
Baden, L
Bayingana, R
Nyombayire, J
Anzala, O
Nyasani, D
Roux, S
Mangenya, N
Laher, F
Mambe, M
Innes, C
Mngadi, K
Walsh, S
Johnson, J
Dolin, R
Stevens, G
Grunenberg, N
Barouch, D
Fast, P
Laufer, D
description Background: Homologous and heterologous prime-boost regimens were compared using two adenovirus vectors (Ad26.EnvA. 01 [Ad26] and Ad35-EnvA [Ad35]) in the USA, East Africa and South Africa. This is the first trial using either vector for an HIV preventive vaccine in Africa. Safety data between these regions were compared.
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source Mary Ann Liebert Online Subscription; Alma/SFX Local Collection
subjects Adenovirus
Human immunodeficiency virus
Retrovirus
title Safety in a Phase 1 Randomized, Double-Blinded, Placebo-Controlled Trial Evaluating Two Adenovirus HIV Vaccines in Three Different Geographic Regions
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