Time in hemodialysis modulates the levels of genetic damage in hemodialysis patients

It is assumed that hemodialysis treatment can diminish the levels of genetic damage in circulating lymphocytes by cleaning the blood of uremic toxins that cause oxidative stress. However, the hemodialysis process by itself may also induce genomic damage by producing reactive oxygen species (ROS). We...

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Veröffentlicht in:	Environmental and molecular mutagenesis 2014-05, Vol.55 (4), p.363-368
Hauptverfasser:	Rodríguez-Ribera, Lara, Stoyanova, Elitsa, Corredor, Zuray, Coll, Elisabet, Silva, Irene, Diaz, Juan Manuel, Ballarin, José, Marcos, Ricard, Pastor, Susana
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Cells, Cultured CRF patients DNA Damage - genetics DNA Damage - radiation effects Female Follow-Up Studies Genomic Instability Humans Kidney Failure, Chronic - blood Kidney Failure, Chronic - genetics Kidney Failure, Chronic - therapy Lymphocytes - metabolism Lymphocytes - pathology Lymphocytes - radiation effects Male micronucleus assay Micronucleus Tests Oxidative Stress - radiation effects radiosensitivity Reactive Oxygen Species - metabolism Renal Dialysis - adverse effects uremic state
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