Cetuximab plus or minus chemotherapy enhances dendritic cell-mediated phagocytosis of colon cancer cells and ignites a highly efficient colon cancer antigen-specific cytotoxic T-cell response in vitro

Cetuximab is a human/mouse chimeric IgG1 monoclonal antibody (mAb) to epidermal growth factor receptor, approved for colorectal carcinoma treatment in combination with chemotherapy. The immune-mediated effects elicited by its human fraction of crystallization moiety might critically contribute to th...

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Veröffentlicht in:	International journal of cancer 2012-04, Vol.130 (7), p.1577-1589
Hauptverfasser:	Correale, P, Botta, C, Cusi, M G, Del Vecchio, MT, De Santi, MM, Gori Savellini, G, Bestoso, E, Apollinari, S, Mannucci, S, Marra, M, Abbruzzese, A, Aquino, A, Turriziani, M, Bonmassar, L, Caraglia, M, Tagliaferri, P
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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