Validation of the 12-Gene Colon Cancer Recurrence Score as a Predictor of Recurrence Risk in Stage II and III Rectal Cancer Patients

The 12-gene Recurrence Score assay is a validated predictor of recurrence risk in stage II and III colon cancer patients. We conducted a prospectively designed study to validate this assay for prediction of recurrence risk in stage II and III rectal cancer patients from the Dutch Total Mesorectal Ex...

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Veröffentlicht in:	JNCI : Journal of the National Cancer Institute 2014-11, Vol.106 (11), p.1
Hauptverfasser:	REIMERS, Marlies S, KUPPEN, Peter J. K, LEE, Mark, LOPATIN, Margarita, TEZCAN, Haluk, PUTTER, Hein, CLARK-LANGONE, Kim, LIEFERS, Gerrit Jan, SHAK, Steve, VAN DE VELDE, Cornelis J. H
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Aged, 80 and over Bioassays Biological and medical sciences Colonic Neoplasms - epidemiology Colonic Neoplasms - genetics Colonic Neoplasms - pathology Colorectal cancer Female Gastroenterology. Liver. Pancreas. Abdomen Gene Expression Profiling Gene Expression Regulation, Neoplastic Genetic Testing Genetics Humans Incidence Kaplan-Meier Estimate Male Medical sciences Middle Aged Multiple tumors. Solid tumors. Tumors in childhood (general aspects) Neoplasm Recurrence, Local - epidemiology Neoplasm Recurrence, Local - genetics Neoplasm Staging Netherlands - epidemiology Odds Ratio Polymerase chain reaction Predictive Value of Tests Prognosis Proportional Hazards Models Prospective Studies Randomized Controlled Trials as Topic Real-Time Polymerase Chain Reaction Rectal Neoplasms - genetics Rectal Neoplasms - pathology Risk factors Stomach. Duodenum. Small intestine. Colon. Rectum. Anus Tumors Validation studies
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