Collagen–poly(dialdehyde) guar gum based porous 3D scaffolds immobilized with growth factor for tissue engineering applications

•Poly(dialdehyde) guar gum (PDAGG) was synthesized by sodium periodate method.•Covalently linked collagen–PDAGG–PDGF based hybrid scaffolds were prepared.•PDAGG stabilizes collagen and crosslinks PDGF by imine bond formation.•In vitro drug release shows the sustained release of PDGF up to 13 days.•E...

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Veröffentlicht in:	Carbohydrate polymers 2014-12, Vol.114, p.399-406
Hauptverfasser:	Ragothaman, Murali, Palanisamy, Thanikaivelan, Kalirajan, Cheirmadurai
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Applied sciences Becaplermin Biocompatible Materials - chemistry Biological and medical sciences Cellularization Collagen Collagen - chemistry Exact sciences and technology Galactans - chemistry Mannans - chemistry Medical sciences Mice Natural polymers NIH 3T3 Cells Physicochemistry of polymers Plant Gums - chemistry Platelet-derived growth factor Poly(dialdehyde) guar gum Porosity Proto-Oncogene Proteins c-sis - chemistry Proto-Oncogene Proteins c-sis - classification Starch and polysaccharides Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases Technology. Biomaterials. Equipments Tissue Engineering - methods Tissue Scaffolds - chemistry
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