Exogenous application of estradiol to eggs unexpectedly induces male development in two turtle species with temperature-dependent sex determination
Highlights • We evaluate the effects of temperature, estradiol, and aromatase inhibition on sex determination. • Aromatase inhibition had no effect on gonadal sex in two turtles with environmental sex determination. • Exogenous application of estradiol to eggs induced male gonad development. • These...
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| Veröffentlicht in: | General and comparative endocrinology 2014-09, Vol.206, p.16-23 |
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| container_title | General and comparative endocrinology |
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| creator | Warner, Daniel A Addis, Elizabeth Du, Wei-guo Wibbels, Thane Janzen, Fredric J |
| description | Highlights • We evaluate the effects of temperature, estradiol, and aromatase inhibition on sex determination. • Aromatase inhibition had no effect on gonadal sex in two turtles with environmental sex determination. • Exogenous application of estradiol to eggs induced male gonad development. • These unexpected results were reproduced in four independent experiments. |
| doi_str_mv | 10.1016/j.ygcen.2014.06.008 |
| format | Article |
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| ispartof | General and comparative endocrinology, 2014-09, Vol.206, p.16-23 |
| issn | 0016-6480 1095-6840 |
| language | eng |
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| source | MEDLINE; Elsevier ScienceDirect Journals |
| subjects | Animals Aromatase - chemistry Aromatase - metabolism Aromatase inhibitor Aromatase Inhibitors - pharmacology Chelydra serpentina Chrysemys picta Endocrinology & Metabolism Environmental sex determination Estradiol - pharmacology Estrogens - pharmacology Female Humans Male Ovary - drug effects Ovum - cytology Ovum - drug effects Ovum - metabolism Sex Determination Analysis Sex Ratio Sex steroids Sexual differentiation Temperature Turtles - physiology |
| title | Exogenous application of estradiol to eggs unexpectedly induces male development in two turtle species with temperature-dependent sex determination |
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