Emerging role of advanced glycation-end products (AGEs) in the pathobiology of eye diseases

Advanced glycation end products (AGEs) have been implicated in vision loss associated with macula degeneration, cataract formation, diabetic retinopathy and glaucoma. This pathogenic potential is mainly attributed to their accumulation in ocular tissues where they mediate aberrant crosslinking of ex...

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Veröffentlicht in:	Progress in retinal and eye research 2014-09, Vol.42, p.85-102
Hauptverfasser:	Kandarakis, Stylianos A., Piperi, Christina, Topouzis, Fotis, Papavassiliou, Athanasios G.
Format:	Artikel
Sprache:	eng
Schlagworte:	AGEs Angiogenesis Anti-glycating agents Blood-retinal barrier Blood-Retinal Barrier - physiopathology Eye disease Eye Diseases - physiopathology Glycation End Products, Advanced - physiology Humans Inflammation Neovascularization, Pathologic - physiopathology Oxidative Stress - physiology
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