The CTLA-4 Gene Region of Chromosome 2q33 Is Linked to, and Associated with, Type 1 Diabetes

Susceptibility to autoimmune insulin-dependent (type 1) diabetes mellitus is determined by a combination of environmental and genetic factors, which include variation in MHC genes on chromosome 6p21 (IDDM1) and the insulin gene on chromosome 11p15 (IDDM2). However, linkage to IDDM1 and IDDM2 cannot...

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Veröffentlicht in:Human molecular genetics 1996-07, Vol.5 (7), p.1075-1080
Hauptverfasser: Nisticò, Lorenza, Buzzetti, Raffaella, Pritchard, Lynn E., Van der Auwera, Bart, Giovannini, Claudio, Bosi, Emanuele, Martinez Larrad, Maria Teresa, Serrano Rios, Manuel, Chow, C. C., Cockram, Clive S., Jacobs, Karen, Mijovic, Catherine, Bain, Stephen C., Barnett, Anthony H., Vandewalle, Christina L., Schuit, Frans, Gorus, Frans K., Tosi, Roberto, Pozzilli, Paolo, Todd, John A.
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Sprache:eng
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