Prevalence of Chronic Kidney Disease in an Adult Population

Background and Aims One strategy to prevent and manage chronic kidney disease (CKD) is to offer screening programs. The aim of this study was to determine the percentage prevalence and risk factors of CKD in a screening program performed in an adult general population. Methods This is a cross-sectio...

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Veröffentlicht in:Archives of medical research 2014-08, Vol.45 (6), p.507-513
Hauptverfasser: Cueto-Manzano, Alfonso M, Cortés-Sanabria, Laura, Martínez-Ramírez, Héctor R, Rojas-Campos, Enrique, Gómez-Navarro, Benjamin, Castillero-Manzano, Marcelo
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container_end_page 513
container_issue 6
container_start_page 507
container_title Archives of medical research
container_volume 45
creator Cueto-Manzano, Alfonso M
Cortés-Sanabria, Laura
Martínez-Ramírez, Héctor R
Rojas-Campos, Enrique
Gómez-Navarro, Benjamin
Castillero-Manzano, Marcelo
description Background and Aims One strategy to prevent and manage chronic kidney disease (CKD) is to offer screening programs. The aim of this study was to determine the percentage prevalence and risk factors of CKD in a screening program performed in an adult general population. Methods This is a cross-sectional study. Six-hundred ten adults (73% women, age 51 ± 14 years) without previously known CKD were evaluated. Participants were subjected to a questionnaire, blood pressure measurement and anthropometry. Glomerular filtration rate estimated by CKD-EPI formula and urine tested with albuminuria dipstick. Results More than 50% of subjects reported family antecedents of diabetes mellitus (DM), hypertension and obesity, and 30% of CKD. DM was self-reported in 19% and hypertension in 29%. During screening, overweight/obesity was found in 75%; women had a higher frequency of obesity (41 vs. 34%) and high-risk abdominal waist circumference (87 vs. 75%) than men. Hypertension (both self-reported and diagnosed in screening) was more frequent in men (49%) than in women (38%). CKD was found in 14.7%: G1, 5.9%; G2, 4.5%; G3a, 2.6%; G3b, 1.1%, G4, 0.3%; and G5, 0.3%. Glomerular filtration rate was mildly/moderately reduced in 2.6%, moderately/severely reduced in 1.1%, and severely reduced in
doi_str_mv 10.1016/j.arcmed.2014.06.007
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The aim of this study was to determine the percentage prevalence and risk factors of CKD in a screening program performed in an adult general population. Methods This is a cross-sectional study. Six-hundred ten adults (73% women, age 51 ± 14 years) without previously known CKD were evaluated. Participants were subjected to a questionnaire, blood pressure measurement and anthropometry. Glomerular filtration rate estimated by CKD-EPI formula and urine tested with albuminuria dipstick. Results More than 50% of subjects reported family antecedents of diabetes mellitus (DM), hypertension and obesity, and 30% of CKD. DM was self-reported in 19% and hypertension in 29%. During screening, overweight/obesity was found in 75%; women had a higher frequency of obesity (41 vs. 34%) and high-risk abdominal waist circumference (87 vs. 75%) than men. Hypertension (both self-reported and diagnosed in screening) was more frequent in men (49%) than in women (38%). CKD was found in 14.7%: G1, 5.9%; G2, 4.5%; G3a, 2.6%; G3b, 1.1%, G4, 0.3%; and G5, 0.3%. Glomerular filtration rate was mildly/moderately reduced in 2.6%, moderately/severely reduced in 1.1%, and severely reduced in &lt;1%. Abnormal albuminuria was found in 13%. CKD was predicted by DM, hypertension and male gender. Conclusions A percentage CKD prevalence of 14.7% was found in this sample of an adult population, with most patients at early stages. Screening programs constitute excellent opportunities in the fight against kidney disease, particularly in populations at high risk.</description><identifier>ISSN: 0188-4409</identifier><identifier>EISSN: 1873-5487</identifier><identifier>DOI: 10.1016/j.arcmed.2014.06.007</identifier><identifier>PMID: 24992221</identifier><language>eng</language><publisher>United States: Elsevier Inc</publisher><subject>Adolescent ; Adult ; Aged ; Aged, 80 and over ; Chronic kidney disease ; Cross-Sectional Studies ; Female ; General population ; Humans ; Internal Medicine ; Kidney Function Tests ; Logistic Models ; Male ; Mass Screening ; Mexico - epidemiology ; Middle Aged ; Prevalence ; Renal Insufficiency, Chronic - diagnosis ; Renal Insufficiency, Chronic - epidemiology ; Renal Insufficiency, Chronic - etiology ; Risk Factors ; Screening ; Young Adult</subject><ispartof>Archives of medical research, 2014-08, Vol.45 (6), p.507-513</ispartof><rights>IMSS</rights><rights>2014 IMSS</rights><rights>Copyright © 2014 IMSS. Published by Elsevier Inc. All rights reserved.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c417t-97e669eefa04c50224b1fac9c8ed45918fcfcca5fe0e4a834a04a700f630071a3</citedby><cites>FETCH-LOGICAL-c417t-97e669eefa04c50224b1fac9c8ed45918fcfcca5fe0e4a834a04a700f630071a3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://dx.doi.org/10.1016/j.arcmed.2014.06.007$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,777,781,3537,27905,27906,45976</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/24992221$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Cueto-Manzano, Alfonso M</creatorcontrib><creatorcontrib>Cortés-Sanabria, Laura</creatorcontrib><creatorcontrib>Martínez-Ramírez, Héctor R</creatorcontrib><creatorcontrib>Rojas-Campos, Enrique</creatorcontrib><creatorcontrib>Gómez-Navarro, Benjamin</creatorcontrib><creatorcontrib>Castillero-Manzano, Marcelo</creatorcontrib><title>Prevalence of Chronic Kidney Disease in an Adult Population</title><title>Archives of medical research</title><addtitle>Arch Med Res</addtitle><description>Background and Aims One strategy to prevent and manage chronic kidney disease (CKD) is to offer screening programs. The aim of this study was to determine the percentage prevalence and risk factors of CKD in a screening program performed in an adult general population. Methods This is a cross-sectional study. Six-hundred ten adults (73% women, age 51 ± 14 years) without previously known CKD were evaluated. Participants were subjected to a questionnaire, blood pressure measurement and anthropometry. Glomerular filtration rate estimated by CKD-EPI formula and urine tested with albuminuria dipstick. Results More than 50% of subjects reported family antecedents of diabetes mellitus (DM), hypertension and obesity, and 30% of CKD. DM was self-reported in 19% and hypertension in 29%. During screening, overweight/obesity was found in 75%; women had a higher frequency of obesity (41 vs. 34%) and high-risk abdominal waist circumference (87 vs. 75%) than men. Hypertension (both self-reported and diagnosed in screening) was more frequent in men (49%) than in women (38%). CKD was found in 14.7%: G1, 5.9%; G2, 4.5%; G3a, 2.6%; G3b, 1.1%, G4, 0.3%; and G5, 0.3%. Glomerular filtration rate was mildly/moderately reduced in 2.6%, moderately/severely reduced in 1.1%, and severely reduced in &lt;1%. Abnormal albuminuria was found in 13%. CKD was predicted by DM, hypertension and male gender. Conclusions A percentage CKD prevalence of 14.7% was found in this sample of an adult population, with most patients at early stages. Screening programs constitute excellent opportunities in the fight against kidney disease, particularly in populations at high risk.</description><subject>Adolescent</subject><subject>Adult</subject><subject>Aged</subject><subject>Aged, 80 and over</subject><subject>Chronic kidney disease</subject><subject>Cross-Sectional Studies</subject><subject>Female</subject><subject>General population</subject><subject>Humans</subject><subject>Internal Medicine</subject><subject>Kidney Function Tests</subject><subject>Logistic Models</subject><subject>Male</subject><subject>Mass Screening</subject><subject>Mexico - epidemiology</subject><subject>Middle Aged</subject><subject>Prevalence</subject><subject>Renal Insufficiency, Chronic - diagnosis</subject><subject>Renal Insufficiency, Chronic - epidemiology</subject><subject>Renal Insufficiency, Chronic - etiology</subject><subject>Risk Factors</subject><subject>Screening</subject><subject>Young Adult</subject><issn>0188-4409</issn><issn>1873-5487</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2014</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkU9r20AQxZeSUjtuv0EJOuYiZUZarSQKBeP8Kw3U0Pa8rFezdB1Z6-xKAX_7rrB9ySUwMId5M4_3G8a-ImQIKG62mfJ6R22WA_IMRAZQfWBzrKsiLXldXbA5YF2nnEMzY5chbAGg5qL6xGY5b5o8z3HOvq09vaqOek2JM8nqn3e91clP2_Z0SG5tIBUosX2i-mTZjt2QrN1-7NRgXf-ZfTSqC_Tl1Bfs7_3dn9Vj-vTr4cdq-ZRqjtWQNhUJ0RAZBVyXkOd8g0bpRtfU8rLB2mijtSoNAXFVFzzqVAVgRBEjoSoW7Pp4d-_dy0hhkDsbNHWd6smNQWIpBGJZxuQLxo9S7V0Inozce7tT_iAR5IRNbuURm5ywSRAyesS1q5PDuJlm56Uzpyj4fhRQzPlqycug7QSttZ70IFtn33N4e0B3NpJW3TMdKGzd6PvIUKIMuQT5e3rd9DnkAFjE-g9JvJOt</recordid><startdate>20140801</startdate><enddate>20140801</enddate><creator>Cueto-Manzano, Alfonso M</creator><creator>Cortés-Sanabria, Laura</creator><creator>Martínez-Ramírez, Héctor R</creator><creator>Rojas-Campos, Enrique</creator><creator>Gómez-Navarro, Benjamin</creator><creator>Castillero-Manzano, Marcelo</creator><general>Elsevier Inc</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20140801</creationdate><title>Prevalence of Chronic Kidney Disease in an Adult Population</title><author>Cueto-Manzano, Alfonso M ; Cortés-Sanabria, Laura ; Martínez-Ramírez, Héctor R ; Rojas-Campos, Enrique ; Gómez-Navarro, Benjamin ; Castillero-Manzano, Marcelo</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c417t-97e669eefa04c50224b1fac9c8ed45918fcfcca5fe0e4a834a04a700f630071a3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2014</creationdate><topic>Adolescent</topic><topic>Adult</topic><topic>Aged</topic><topic>Aged, 80 and over</topic><topic>Chronic kidney disease</topic><topic>Cross-Sectional Studies</topic><topic>Female</topic><topic>General population</topic><topic>Humans</topic><topic>Internal Medicine</topic><topic>Kidney Function Tests</topic><topic>Logistic Models</topic><topic>Male</topic><topic>Mass Screening</topic><topic>Mexico - epidemiology</topic><topic>Middle Aged</topic><topic>Prevalence</topic><topic>Renal Insufficiency, Chronic - diagnosis</topic><topic>Renal Insufficiency, Chronic - epidemiology</topic><topic>Renal Insufficiency, Chronic - etiology</topic><topic>Risk Factors</topic><topic>Screening</topic><topic>Young Adult</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Cueto-Manzano, Alfonso M</creatorcontrib><creatorcontrib>Cortés-Sanabria, Laura</creatorcontrib><creatorcontrib>Martínez-Ramírez, Héctor R</creatorcontrib><creatorcontrib>Rojas-Campos, Enrique</creatorcontrib><creatorcontrib>Gómez-Navarro, Benjamin</creatorcontrib><creatorcontrib>Castillero-Manzano, Marcelo</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Archives of medical research</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Cueto-Manzano, Alfonso M</au><au>Cortés-Sanabria, Laura</au><au>Martínez-Ramírez, Héctor R</au><au>Rojas-Campos, Enrique</au><au>Gómez-Navarro, Benjamin</au><au>Castillero-Manzano, Marcelo</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Prevalence of Chronic Kidney Disease in an Adult Population</atitle><jtitle>Archives of medical research</jtitle><addtitle>Arch Med Res</addtitle><date>2014-08-01</date><risdate>2014</risdate><volume>45</volume><issue>6</issue><spage>507</spage><epage>513</epage><pages>507-513</pages><issn>0188-4409</issn><eissn>1873-5487</eissn><abstract>Background and Aims One strategy to prevent and manage chronic kidney disease (CKD) is to offer screening programs. The aim of this study was to determine the percentage prevalence and risk factors of CKD in a screening program performed in an adult general population. Methods This is a cross-sectional study. Six-hundred ten adults (73% women, age 51 ± 14 years) without previously known CKD were evaluated. Participants were subjected to a questionnaire, blood pressure measurement and anthropometry. Glomerular filtration rate estimated by CKD-EPI formula and urine tested with albuminuria dipstick. Results More than 50% of subjects reported family antecedents of diabetes mellitus (DM), hypertension and obesity, and 30% of CKD. DM was self-reported in 19% and hypertension in 29%. During screening, overweight/obesity was found in 75%; women had a higher frequency of obesity (41 vs. 34%) and high-risk abdominal waist circumference (87 vs. 75%) than men. Hypertension (both self-reported and diagnosed in screening) was more frequent in men (49%) than in women (38%). CKD was found in 14.7%: G1, 5.9%; G2, 4.5%; G3a, 2.6%; G3b, 1.1%, G4, 0.3%; and G5, 0.3%. Glomerular filtration rate was mildly/moderately reduced in 2.6%, moderately/severely reduced in 1.1%, and severely reduced in &lt;1%. Abnormal albuminuria was found in 13%. CKD was predicted by DM, hypertension and male gender. Conclusions A percentage CKD prevalence of 14.7% was found in this sample of an adult population, with most patients at early stages. Screening programs constitute excellent opportunities in the fight against kidney disease, particularly in populations at high risk.</abstract><cop>United States</cop><pub>Elsevier Inc</pub><pmid>24992221</pmid><doi>10.1016/j.arcmed.2014.06.007</doi><tpages>7</tpages></addata></record>
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subjects Adolescent
Adult
Aged
Aged, 80 and over
Chronic kidney disease
Cross-Sectional Studies
Female
General population
Humans
Internal Medicine
Kidney Function Tests
Logistic Models
Male
Mass Screening
Mexico - epidemiology
Middle Aged
Prevalence
Renal Insufficiency, Chronic - diagnosis
Renal Insufficiency, Chronic - epidemiology
Renal Insufficiency, Chronic - etiology
Risk Factors
Screening
Young Adult
title Prevalence of Chronic Kidney Disease in an Adult Population
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