Utilization of Vascular Conduits to Facilitate Renal Transplantation in Patients With Significant Aortoiliac Calcification
Objective To describe the use of vascular conduits (donor iliac artery or saphenous vein) in renal transplantation recipients with extensive aortoiliac calcification. Materials and Methods Vascular conduits were used in 10 renal transplants with severe vascular calcification at Cleveland Clinic from...
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Veröffentlicht in: | Urology (Ridgewood, N.J.) N.J.), 2014-10, Vol.84 (4), p.967-970 |
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description | Objective To describe the use of vascular conduits (donor iliac artery or saphenous vein) in renal transplantation recipients with extensive aortoiliac calcification. Materials and Methods Vascular conduits were used in 10 renal transplants with severe vascular calcification at Cleveland Clinic from 2009 to 2013. Both iliac artery (N = 8) and saphenous vein (N = 2) grafts were used. Surgical technique is reviewed in detail. Surgical complications, patency on renal transplant ultrasonography, and serum creatinine level at multiple time points were reviewed. Results Mean follow-up time was 26 months (7-44 months). Mean serum creatinine level was 1.42 mg/dL (1.04-1.74 mg/dL) at 6 months, 1.35 mg/dL (0.83-1.86 mg/dL) at 12 months, and 1.43 mg/dL (0.79-1.81 mg/dL) at last follow-up. All patients were demonstrated postoperatively to have patent vasculature on renal ultrasonography. No patients experienced lower extremity vascular complications. Death-censored graft survival was 100%. One patient died from complications after mitral valve replacement, and one patient died from metastatic squamous cell carcinoma of the tongue. Both patients had functioning grafts at the time of death. Conclusion Vascular conduits can be used to facilitate renal transplantation in the setting of severe recipient aortoiliac calcification, thus allowing for successful transplantation of these complex recipients. |
doi_str_mv | 10.1016/j.urology.2014.07.026 |
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Materials and Methods Vascular conduits were used in 10 renal transplants with severe vascular calcification at Cleveland Clinic from 2009 to 2013. Both iliac artery (N = 8) and saphenous vein (N = 2) grafts were used. Surgical technique is reviewed in detail. Surgical complications, patency on renal transplant ultrasonography, and serum creatinine level at multiple time points were reviewed. Results Mean follow-up time was 26 months (7-44 months). Mean serum creatinine level was 1.42 mg/dL (1.04-1.74 mg/dL) at 6 months, 1.35 mg/dL (0.83-1.86 mg/dL) at 12 months, and 1.43 mg/dL (0.79-1.81 mg/dL) at last follow-up. All patients were demonstrated postoperatively to have patent vasculature on renal ultrasonography. No patients experienced lower extremity vascular complications. Death-censored graft survival was 100%. One patient died from complications after mitral valve replacement, and one patient died from metastatic squamous cell carcinoma of the tongue. Both patients had functioning grafts at the time of death. Conclusion Vascular conduits can be used to facilitate renal transplantation in the setting of severe recipient aortoiliac calcification, thus allowing for successful transplantation of these complex recipients.</description><identifier>ISSN: 0090-4295</identifier><identifier>EISSN: 1527-9995</identifier><identifier>DOI: 10.1016/j.urology.2014.07.026</identifier><identifier>PMID: 25260455</identifier><language>eng</language><publisher>United States: Elsevier Inc</publisher><subject>Aged ; Aortic Diseases - surgery ; Female ; Humans ; Iliac Artery - transplantation ; Kidney Transplantation - methods ; Male ; Middle Aged ; Retrospective Studies ; Saphenous Vein - transplantation ; Severity of Illness Index ; Urology ; Vascular Calcification - surgery ; Vascular Grafting</subject><ispartof>Urology (Ridgewood, N.J.), 2014-10, Vol.84 (4), p.967-970</ispartof><rights>Elsevier Inc.</rights><rights>2014 Elsevier Inc.</rights><rights>Copyright © 2014 Elsevier Inc. All rights reserved.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c420t-fb17ba22f2c9d53f90af96f4af3dc4a1dbc65dbedd402bc709d66290196c85bc3</citedby><cites>FETCH-LOGICAL-c420t-fb17ba22f2c9d53f90af96f4af3dc4a1dbc65dbedd402bc709d66290196c85bc3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://dx.doi.org/10.1016/j.urology.2014.07.026$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,780,784,3550,27924,27925,45995</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/25260455$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Coleman, Sarah</creatorcontrib><creatorcontrib>Kerr, Hannah</creatorcontrib><creatorcontrib>Goldfarb, David</creatorcontrib><creatorcontrib>Krishnamurthi, Venkatesh</creatorcontrib><creatorcontrib>Rabets, John C</creatorcontrib><title>Utilization of Vascular Conduits to Facilitate Renal Transplantation in Patients With Significant Aortoiliac Calcification</title><title>Urology (Ridgewood, N.J.)</title><addtitle>Urology</addtitle><description>Objective To describe the use of vascular conduits (donor iliac artery or saphenous vein) in renal transplantation recipients with extensive aortoiliac calcification. Materials and Methods Vascular conduits were used in 10 renal transplants with severe vascular calcification at Cleveland Clinic from 2009 to 2013. Both iliac artery (N = 8) and saphenous vein (N = 2) grafts were used. Surgical technique is reviewed in detail. Surgical complications, patency on renal transplant ultrasonography, and serum creatinine level at multiple time points were reviewed. Results Mean follow-up time was 26 months (7-44 months). Mean serum creatinine level was 1.42 mg/dL (1.04-1.74 mg/dL) at 6 months, 1.35 mg/dL (0.83-1.86 mg/dL) at 12 months, and 1.43 mg/dL (0.79-1.81 mg/dL) at last follow-up. All patients were demonstrated postoperatively to have patent vasculature on renal ultrasonography. No patients experienced lower extremity vascular complications. Death-censored graft survival was 100%. One patient died from complications after mitral valve replacement, and one patient died from metastatic squamous cell carcinoma of the tongue. Both patients had functioning grafts at the time of death. Conclusion Vascular conduits can be used to facilitate renal transplantation in the setting of severe recipient aortoiliac calcification, thus allowing for successful transplantation of these complex recipients.</description><subject>Aged</subject><subject>Aortic Diseases - surgery</subject><subject>Female</subject><subject>Humans</subject><subject>Iliac Artery - transplantation</subject><subject>Kidney Transplantation - methods</subject><subject>Male</subject><subject>Middle Aged</subject><subject>Retrospective Studies</subject><subject>Saphenous Vein - transplantation</subject><subject>Severity of Illness Index</subject><subject>Urology</subject><subject>Vascular Calcification - surgery</subject><subject>Vascular Grafting</subject><issn>0090-4295</issn><issn>1527-9995</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2014</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkc9vFCEUx4nR2G31T9Bw9DLjgxmYctE0G2tNmmhsq0fC8KOyssMKjMn2r5dxVw9ePEHI5_se7_MQekGgJUD46007pxji_b6lQPoWhhYof4RWhNGhEUKwx2gFIKDpqWAn6DTnDQBwzoen6IQyyqFnbIUe7ooP_kEVHyccHf6isp6DSngdJzP7knGJ-FLpChVVLP5sJxXwbVJT3gU1lUPQT_hTvdmp8l99-YZv_P3kndeVwBcxlVjzSuO1Cvr385J6hp44FbJ9fjzP0N3lu9v1VXP98f2H9cV1o3sKpXEjGUZFqaNaGNY5AcoJ7nrlOqN7RcyoOTOjNaYHOuoBhOGcCiCC63M26u4MvTrU3aX4Y7a5yK3P2ob6fRvnLAnjnBDad-cVZQdUp5hzsk7ukt-qtJcE5KJdbuRRu1y0Sxhk1V5zL48t5nFrzd_UH88VeHsAbB30p7dJZl11aWt8srpIE_1_W7z5p4IOfqoqw3e7t3kT51Q3U6eRmUqQN8vul9WTHmCoIrtftLOu4A</recordid><startdate>20141001</startdate><enddate>20141001</enddate><creator>Coleman, Sarah</creator><creator>Kerr, Hannah</creator><creator>Goldfarb, David</creator><creator>Krishnamurthi, Venkatesh</creator><creator>Rabets, John C</creator><general>Elsevier Inc</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20141001</creationdate><title>Utilization of Vascular Conduits to Facilitate Renal Transplantation in Patients With Significant Aortoiliac Calcification</title><author>Coleman, Sarah ; Kerr, Hannah ; Goldfarb, David ; Krishnamurthi, Venkatesh ; Rabets, John C</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c420t-fb17ba22f2c9d53f90af96f4af3dc4a1dbc65dbedd402bc709d66290196c85bc3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2014</creationdate><topic>Aged</topic><topic>Aortic Diseases - surgery</topic><topic>Female</topic><topic>Humans</topic><topic>Iliac Artery - transplantation</topic><topic>Kidney Transplantation - methods</topic><topic>Male</topic><topic>Middle Aged</topic><topic>Retrospective Studies</topic><topic>Saphenous Vein - transplantation</topic><topic>Severity of Illness Index</topic><topic>Urology</topic><topic>Vascular Calcification - surgery</topic><topic>Vascular Grafting</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Coleman, Sarah</creatorcontrib><creatorcontrib>Kerr, Hannah</creatorcontrib><creatorcontrib>Goldfarb, David</creatorcontrib><creatorcontrib>Krishnamurthi, Venkatesh</creatorcontrib><creatorcontrib>Rabets, John C</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Urology (Ridgewood, N.J.)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Coleman, Sarah</au><au>Kerr, Hannah</au><au>Goldfarb, David</au><au>Krishnamurthi, Venkatesh</au><au>Rabets, John C</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Utilization of Vascular Conduits to Facilitate Renal Transplantation in Patients With Significant Aortoiliac Calcification</atitle><jtitle>Urology (Ridgewood, N.J.)</jtitle><addtitle>Urology</addtitle><date>2014-10-01</date><risdate>2014</risdate><volume>84</volume><issue>4</issue><spage>967</spage><epage>970</epage><pages>967-970</pages><issn>0090-4295</issn><eissn>1527-9995</eissn><abstract>Objective To describe the use of vascular conduits (donor iliac artery or saphenous vein) in renal transplantation recipients with extensive aortoiliac calcification. Materials and Methods Vascular conduits were used in 10 renal transplants with severe vascular calcification at Cleveland Clinic from 2009 to 2013. Both iliac artery (N = 8) and saphenous vein (N = 2) grafts were used. Surgical technique is reviewed in detail. Surgical complications, patency on renal transplant ultrasonography, and serum creatinine level at multiple time points were reviewed. Results Mean follow-up time was 26 months (7-44 months). Mean serum creatinine level was 1.42 mg/dL (1.04-1.74 mg/dL) at 6 months, 1.35 mg/dL (0.83-1.86 mg/dL) at 12 months, and 1.43 mg/dL (0.79-1.81 mg/dL) at last follow-up. All patients were demonstrated postoperatively to have patent vasculature on renal ultrasonography. No patients experienced lower extremity vascular complications. Death-censored graft survival was 100%. One patient died from complications after mitral valve replacement, and one patient died from metastatic squamous cell carcinoma of the tongue. Both patients had functioning grafts at the time of death. Conclusion Vascular conduits can be used to facilitate renal transplantation in the setting of severe recipient aortoiliac calcification, thus allowing for successful transplantation of these complex recipients.</abstract><cop>United States</cop><pub>Elsevier Inc</pub><pmid>25260455</pmid><doi>10.1016/j.urology.2014.07.026</doi><tpages>4</tpages></addata></record> |
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subjects | Aged Aortic Diseases - surgery Female Humans Iliac Artery - transplantation Kidney Transplantation - methods Male Middle Aged Retrospective Studies Saphenous Vein - transplantation Severity of Illness Index Urology Vascular Calcification - surgery Vascular Grafting |
title | Utilization of Vascular Conduits to Facilitate Renal Transplantation in Patients With Significant Aortoiliac Calcification |
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