Metacognitive therapy versus cognitive behavioural therapy for depression: a randomized pilot study

Objective: Metacognitive therapy (MCT) is one of the newer developments within cognitive therapy. This randomized controlled pilot study compared independently applied MCT with cognitive behavioural therapy (CBT) in outpatients with depression to explore the relative speed and efficacy of MCT, ahead...

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Veröffentlicht in:Australian and New Zealand journal of psychiatry 2014-10, Vol.48 (10), p.932-943
Hauptverfasser: Jordan, Jennifer, Carter, Janet D, McIntosh, Virginia VW, Fernando, Kumari, Frampton, Christopher MA, Porter, Richard J, Mulder, Roger T, Lacey, Cameron, Joyce, Peter R
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container_end_page 943
container_issue 10
container_start_page 932
container_title Australian and New Zealand journal of psychiatry
container_volume 48
creator Jordan, Jennifer
Carter, Janet D
McIntosh, Virginia VW
Fernando, Kumari
Frampton, Christopher MA
Porter, Richard J
Mulder, Roger T
Lacey, Cameron
Joyce, Peter R
description Objective: Metacognitive therapy (MCT) is one of the newer developments within cognitive therapy. This randomized controlled pilot study compared independently applied MCT with cognitive behavioural therapy (CBT) in outpatients with depression to explore the relative speed and efficacy of MCT, ahead of a planned randomized controlled trial. Method: A total of 48 participants referred for outpatient therapy were randomized to up to 12 weeks of MCT or CBT. Key outcomes were reduction in depressive symptoms at week 4 and week 12, measured using the independent-clinician-rated Quick Inventory of Depressive Symptomatology16. Intention-to-treat and completer analyses as well as additional methods of reporting outcome of depression are presented. Results: Both therapies were effective in producing clinically significant change in depressive symptoms, with moderate-to-large effect sizes obtained. No differences were detected between therapies in overall outcome or early change on clinician-rated or self-reported measures. Post-hoc analyses suggest that MCT may have been adversely affected by greater comorbidity. Conclusions: In this large pilot study conducted independently of MCT’s developers, MCT was an effective treatment for outpatients with depression, with similar results overall to CBT. Insufficient power and imbalanced comorbidity limit conclusions regarding comparative efficacy so further studies of MCT and CBT are required.
doi_str_mv 10.1177/0004867414533015
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Post-hoc analyses suggest that MCT may have been adversely affected by greater comorbidity. Conclusions: In this large pilot study conducted independently of MCT’s developers, MCT was an effective treatment for outpatients with depression, with similar results overall to CBT. Insufficient power and imbalanced comorbidity limit conclusions regarding comparative efficacy so further studies of MCT and CBT are required.</description><identifier>ISSN: 0004-8674</identifier><identifier>EISSN: 1440-1614</identifier><identifier>DOI: 10.1177/0004867414533015</identifier><identifier>PMID: 24810871</identifier><identifier>CODEN: ANZPBQ</identifier><language>eng</language><publisher>London, England: SAGE Publications</publisher><subject>Adolescent ; Adult ; Adult and adolescent clinical studies ; Aged ; Behavior therapy ; Behavior therapy. 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Post-hoc analyses suggest that MCT may have been adversely affected by greater comorbidity. Conclusions: In this large pilot study conducted independently of MCT’s developers, MCT was an effective treatment for outpatients with depression, with similar results overall to CBT. Insufficient power and imbalanced comorbidity limit conclusions regarding comparative efficacy so further studies of MCT and CBT are required.</description><subject>Adolescent</subject><subject>Adult</subject><subject>Adult and adolescent clinical studies</subject><subject>Aged</subject><subject>Behavior therapy</subject><subject>Behavior therapy. 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Cognitive therapy</topic><topic>Biological and medical sciences</topic><topic>Bipolar Disorder - therapy</topic><topic>Cognitive therapy</topic><topic>Cognitive Therapy - methods</topic><topic>Depression</topic><topic>Depression, Mental</topic><topic>Depressive Disorder, Major - therapy</topic><topic>Evaluation</topic><topic>Female</topic><topic>Humans</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Middle Aged</topic><topic>Miscellaneous</topic><topic>Mood disorders</topic><topic>Pilot Projects</topic><topic>Psychiatry</topic><topic>Psychology. Psychoanalysis. Psychiatry</topic><topic>Psychopathology. Psychiatry</topic><topic>Treatment</topic><topic>Treatment Outcome</topic><topic>Treatments</topic><topic>Young Adult</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Jordan, Jennifer</creatorcontrib><creatorcontrib>Carter, Janet D</creatorcontrib><creatorcontrib>McIntosh, Virginia VW</creatorcontrib><creatorcontrib>Fernando, Kumari</creatorcontrib><creatorcontrib>Frampton, Christopher MA</creatorcontrib><creatorcontrib>Porter, Richard J</creatorcontrib><creatorcontrib>Mulder, Roger T</creatorcontrib><creatorcontrib>Lacey, Cameron</creatorcontrib><creatorcontrib>Joyce, Peter R</creatorcontrib><collection>Index New Zealand (A&amp;I)</collection><collection>Index New Zealand</collection><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Australian and New Zealand journal of psychiatry</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Jordan, Jennifer</au><au>Carter, Janet D</au><au>McIntosh, Virginia VW</au><au>Fernando, Kumari</au><au>Frampton, Christopher MA</au><au>Porter, Richard J</au><au>Mulder, Roger T</au><au>Lacey, Cameron</au><au>Joyce, Peter R</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Metacognitive therapy versus cognitive behavioural therapy for depression: a randomized pilot study</atitle><jtitle>Australian and New Zealand journal of psychiatry</jtitle><addtitle>Aust N Z J Psychiatry</addtitle><date>2014-10-01</date><risdate>2014</risdate><volume>48</volume><issue>10</issue><spage>932</spage><epage>943</epage><pages>932-943</pages><issn>0004-8674</issn><eissn>1440-1614</eissn><coden>ANZPBQ</coden><abstract>Objective: Metacognitive therapy (MCT) is one of the newer developments within cognitive therapy. 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Post-hoc analyses suggest that MCT may have been adversely affected by greater comorbidity. Conclusions: In this large pilot study conducted independently of MCT’s developers, MCT was an effective treatment for outpatients with depression, with similar results overall to CBT. Insufficient power and imbalanced comorbidity limit conclusions regarding comparative efficacy so further studies of MCT and CBT are required.</abstract><cop>London, England</cop><pub>SAGE Publications</pub><pmid>24810871</pmid><doi>10.1177/0004867414533015</doi><tpages>12</tpages></addata></record>
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source MEDLINE; SAGE Journals
subjects Adolescent
Adult
Adult and adolescent clinical studies
Aged
Behavior therapy
Behavior therapy. Cognitive therapy
Biological and medical sciences
Bipolar Disorder - therapy
Cognitive therapy
Cognitive Therapy - methods
Depression
Depression, Mental
Depressive Disorder, Major - therapy
Evaluation
Female
Humans
Male
Medical sciences
Middle Aged
Miscellaneous
Mood disorders
Pilot Projects
Psychiatry
Psychology. Psychoanalysis. Psychiatry
Psychopathology. Psychiatry
Treatment
Treatment Outcome
Treatments
Young Adult
title Metacognitive therapy versus cognitive behavioural therapy for depression: a randomized pilot study
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