A protective effect after clearance of orthotopic rat hepatocellular carcinoma by nanosecond pulsed electric fields

Abstract Strategies for treating liver cancer using radiation, chemotherapy combinations and tyrosine kinase inhibitors targeting specific mutations have provided longer survival times, yet multiple treatments are often needed and recurrences with new malignant phenotypes are not uncommon. New and i...

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Veröffentlicht in:	European journal of cancer (1990) 2014-10, Vol.50 (15), p.2705-2713
Hauptverfasser:	Chen, Ru, Sain, Nova M, Harlow, K. Tyler, Chen, Yeong-Jer, Shires, Peter K, Heller, Richard, Beebe, Stephen J
Format:	Artikel
Sprache:	eng
Schlagworte:	Absence of recurrence Animals Apoptosis Biological and medical sciences Cancer ablation Carcinoma, Hepatocellular - metabolism Carcinoma, Hepatocellular - pathology Carcinoma, Hepatocellular - therapy Caspase 3 - metabolism Caspase 9 - metabolism Cell Line, Tumor Disease Models, Animal Electroporation Granzyme B Granzymes - metabolism Hematology, Oncology and Palliative Medicine Hepatocellular carcinoma Humans Immunity Liver Neoplasms - metabolism Liver Neoplasms - pathology Liver Neoplasms - therapy Medical sciences Multiple tumors. Solid tumors. Tumors in childhood (general aspects) Nanosecond pulsed electric fields Non-thermal Orthotopic model Pharmacology. Drug treatments Protective Factors Pulsed Radiofrequency Treatment - methods Rats, Sprague-Dawley T-Lymphocytes - metabolism Time Factors Treatment Outcome Tumors
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