Mutagenesis by hydrogen peroxide treatment of mammalian cells: a molecular analysis

Hydrogen peroxide is an oxidizing agent which can be generated intracellularly either during normal metabolism or by treatment with external agents including solar UV radiation. Simian cells (CV-1) transfected with the SV40-based shuttle vector plasmid pZ189 have been treated with H2O2 and then incu...

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Veröffentlicht in:	Carcinogenesis (New York) 1990-02, Vol.11 (2), p.283-293
Hauptverfasser:	Moraes, E.C., Keyse, S.M., Tyrrell, R.M.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Base Composition Base Sequence Biological and medical sciences Cell Line Chemical mutagenesis Chromosome Deletion DNA - drug effects Hydrogen Peroxide - toxicity Medical sciences Molecular Sequence Data Mutation Repetitive Sequences, Nucleic Acid Toxicology
Online-Zugang:	Volltext
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