The interaction of clonidine and nitric oxide on feeding behavior in the chicken
Central administration of α 2-receptor agonists stimulate food intake in mammalian and avian species. Recently we reported that inhibition of nitric oxide (NO) synthase (NOS) decreased food intake in chickens. In the present study, we investigated whether the increased eating induced by clonidine (C...
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| Veröffentlicht in: | Brain research 1995-11, Vol.699 (1), p.161-164 |
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| creator | Choi, Yang-Ho Furuse, Mitsuhiro Okumura, Jun-ichi Michael Denbow, D. |
| description | Central administration of
α
2-receptor
agonists stimulate food intake in mammalian and avian species. Recently we reported that inhibition of nitric oxide (NO) synthase (NOS) decreased food intake in chickens. In the present study, we investigated whether the increased eating induced by clonidine (Clon), and
α
2-receptor
agonist, is attenuated by NOS inhibition. In the first experiment, four levels (0, 9.4, 18.8 or 37.5 nmol/10 μl) of Clon were administered into the right lateral ventricle of chickens, and food intake was monitored. Clon increased 30 min-food intake in a dose-dependent manner. In a co-administration study of
l-
N
G-nitro-arginine methyl ester HCl (LNNA), a NOS inhibitor, and Clon, LNNA (0, 1.5, 3.0 or 5.9 μmol) attenuated food intake induced by Clon (37.5 nmol) in a dose-dependent manner. Our results suggest the possibility that NO interacts with adrenergic neurons in the central nervous system to modulate feeding behavior in the chicken. |
| doi_str_mv | 10.1016/0006-8993(95)01057-3 |
| format | Article |
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α
2-receptor
agonists stimulate food intake in mammalian and avian species. Recently we reported that inhibition of nitric oxide (NO) synthase (NOS) decreased food intake in chickens. In the present study, we investigated whether the increased eating induced by clonidine (Clon), and
α
2-receptor
agonist, is attenuated by NOS inhibition. In the first experiment, four levels (0, 9.4, 18.8 or 37.5 nmol/10 μl) of Clon were administered into the right lateral ventricle of chickens, and food intake was monitored. Clon increased 30 min-food intake in a dose-dependent manner. In a co-administration study of
l-
N
G-nitro-arginine methyl ester HCl (LNNA), a NOS inhibitor, and Clon, LNNA (0, 1.5, 3.0 or 5.9 μmol) attenuated food intake induced by Clon (37.5 nmol) in a dose-dependent manner. Our results suggest the possibility that NO interacts with adrenergic neurons in the central nervous system to modulate feeding behavior in the chicken.</description><identifier>ISSN: 0006-8993</identifier><identifier>EISSN: 1872-6240</identifier><identifier>DOI: 10.1016/0006-8993(95)01057-3</identifier><identifier>PMID: 8616609</identifier><identifier>CODEN: BRREAP</identifier><language>eng</language><publisher>London: Elsevier B.V</publisher><subject>Animals ; Biological and medical sciences ; Chicken ; Chickens ; Clonidine - pharmacology ; Clonidine HCl ; Dose-Response Relationship, Drug ; Drug Interactions ; Eating - drug effects ; Esters - pharmacology ; Feeding behavior ; Feeding. Feeding behavior ; Female ; Fundamental and applied biological sciences. Psychology ; l- NG-nitro-arginine methyl ester HCl (LNNA) ; Male ; Nitric oxide ; Nitric Oxide - pharmacology ; Vertebrates: anatomy and physiology, studies on body, several organs or systems</subject><ispartof>Brain research, 1995-11, Vol.699 (1), p.161-164</ispartof><rights>1995 Elsevier Science B.V. All rights reserved</rights><rights>1996 INIST-CNRS</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c483t-d0d92e8df2deaef3d31e18658335e81e55fb16300af9867c7bcfbf3318aaaf683</citedby><cites>FETCH-LOGICAL-c483t-d0d92e8df2deaef3d31e18658335e81e55fb16300af9867c7bcfbf3318aaaf683</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://www.sciencedirect.com/science/article/pii/0006899395010573$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,776,780,3537,27901,27902,65306</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=2909547$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/8616609$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Choi, Yang-Ho</creatorcontrib><creatorcontrib>Furuse, Mitsuhiro</creatorcontrib><creatorcontrib>Okumura, Jun-ichi</creatorcontrib><creatorcontrib>Michael Denbow, D.</creatorcontrib><title>The interaction of clonidine and nitric oxide on feeding behavior in the chicken</title><title>Brain research</title><addtitle>Brain Res</addtitle><description>Central administration of
α
2-receptor
agonists stimulate food intake in mammalian and avian species. Recently we reported that inhibition of nitric oxide (NO) synthase (NOS) decreased food intake in chickens. In the present study, we investigated whether the increased eating induced by clonidine (Clon), and
α
2-receptor
agonist, is attenuated by NOS inhibition. In the first experiment, four levels (0, 9.4, 18.8 or 37.5 nmol/10 μl) of Clon were administered into the right lateral ventricle of chickens, and food intake was monitored. Clon increased 30 min-food intake in a dose-dependent manner. In a co-administration study of
l-
N
G-nitro-arginine methyl ester HCl (LNNA), a NOS inhibitor, and Clon, LNNA (0, 1.5, 3.0 or 5.9 μmol) attenuated food intake induced by Clon (37.5 nmol) in a dose-dependent manner. Our results suggest the possibility that NO interacts with adrenergic neurons in the central nervous system to modulate feeding behavior in the chicken.</description><subject>Animals</subject><subject>Biological and medical sciences</subject><subject>Chicken</subject><subject>Chickens</subject><subject>Clonidine - pharmacology</subject><subject>Clonidine HCl</subject><subject>Dose-Response Relationship, Drug</subject><subject>Drug Interactions</subject><subject>Eating - drug effects</subject><subject>Esters - pharmacology</subject><subject>Feeding behavior</subject><subject>Feeding. Feeding behavior</subject><subject>Female</subject><subject>Fundamental and applied biological sciences. Psychology</subject><subject>l- NG-nitro-arginine methyl ester HCl (LNNA)</subject><subject>Male</subject><subject>Nitric oxide</subject><subject>Nitric Oxide - pharmacology</subject><subject>Vertebrates: anatomy and physiology, studies on body, several organs or systems</subject><issn>0006-8993</issn><issn>1872-6240</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1995</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kEFPHCEYhkmj0a3tP9CEgzH1MBWGgYGLiTGtNTGxB3smDHy46CwozG7038u6mz32RL68z_uGPAgdU_KTEiouCCGikUqxH4qfE0p437AvaEZl3zai7cgemu2QQ_S1lKd6MqbIATqQggpB1Az9fZgDDnGCbOwUUsTJYzumGFyIgE10OIYpB4vTW3CAK-ABavaIB5ibVUi5tvFUR-w82GeI39C-N2OB79v3CP37_evh-k9zd39ze31119hOsqlxxKkWpPOtAwOeOUaBSsElYxwkBc79QAUjxHglRW_7wfrBM0alMcYLyY7Q2Wb3JafXJZRJL0KxMI4mQloWTbnohOpEBbsNaHMqJYPXLzksTH7XlOi1SL22pNeWtOL6U6RmtXay3V8OC3C70tZczU-3uSnWjD6baEPZYa0iind9xS43GFQXqwBZFxsg2uowg520S-H___gAYa2PCA</recordid><startdate>19951113</startdate><enddate>19951113</enddate><creator>Choi, Yang-Ho</creator><creator>Furuse, Mitsuhiro</creator><creator>Okumura, Jun-ichi</creator><creator>Michael Denbow, D.</creator><general>Elsevier B.V</general><general>Elsevier</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7QG</scope><scope>7TK</scope></search><sort><creationdate>19951113</creationdate><title>The interaction of clonidine and nitric oxide on feeding behavior in the chicken</title><author>Choi, Yang-Ho ; Furuse, Mitsuhiro ; Okumura, Jun-ichi ; Michael Denbow, D.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c483t-d0d92e8df2deaef3d31e18658335e81e55fb16300af9867c7bcfbf3318aaaf683</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1995</creationdate><topic>Animals</topic><topic>Biological and medical sciences</topic><topic>Chicken</topic><topic>Chickens</topic><topic>Clonidine - pharmacology</topic><topic>Clonidine HCl</topic><topic>Dose-Response Relationship, Drug</topic><topic>Drug Interactions</topic><topic>Eating - drug effects</topic><topic>Esters - pharmacology</topic><topic>Feeding behavior</topic><topic>Feeding. Feeding behavior</topic><topic>Female</topic><topic>Fundamental and applied biological sciences. Psychology</topic><topic>l- NG-nitro-arginine methyl ester HCl (LNNA)</topic><topic>Male</topic><topic>Nitric oxide</topic><topic>Nitric Oxide - pharmacology</topic><topic>Vertebrates: anatomy and physiology, studies on body, several organs or systems</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Choi, Yang-Ho</creatorcontrib><creatorcontrib>Furuse, Mitsuhiro</creatorcontrib><creatorcontrib>Okumura, Jun-ichi</creatorcontrib><creatorcontrib>Michael Denbow, D.</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Animal Behavior Abstracts</collection><collection>Neurosciences Abstracts</collection><jtitle>Brain research</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Choi, Yang-Ho</au><au>Furuse, Mitsuhiro</au><au>Okumura, Jun-ichi</au><au>Michael Denbow, D.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>The interaction of clonidine and nitric oxide on feeding behavior in the chicken</atitle><jtitle>Brain research</jtitle><addtitle>Brain Res</addtitle><date>1995-11-13</date><risdate>1995</risdate><volume>699</volume><issue>1</issue><spage>161</spage><epage>164</epage><pages>161-164</pages><issn>0006-8993</issn><eissn>1872-6240</eissn><coden>BRREAP</coden><abstract>Central administration of
α
2-receptor
agonists stimulate food intake in mammalian and avian species. Recently we reported that inhibition of nitric oxide (NO) synthase (NOS) decreased food intake in chickens. In the present study, we investigated whether the increased eating induced by clonidine (Clon), and
α
2-receptor
agonist, is attenuated by NOS inhibition. In the first experiment, four levels (0, 9.4, 18.8 or 37.5 nmol/10 μl) of Clon were administered into the right lateral ventricle of chickens, and food intake was monitored. Clon increased 30 min-food intake in a dose-dependent manner. In a co-administration study of
l-
N
G-nitro-arginine methyl ester HCl (LNNA), a NOS inhibitor, and Clon, LNNA (0, 1.5, 3.0 or 5.9 μmol) attenuated food intake induced by Clon (37.5 nmol) in a dose-dependent manner. Our results suggest the possibility that NO interacts with adrenergic neurons in the central nervous system to modulate feeding behavior in the chicken.</abstract><cop>London</cop><cop>Amsterdam</cop><cop>New York, NY</cop><pub>Elsevier B.V</pub><pmid>8616609</pmid><doi>10.1016/0006-8993(95)01057-3</doi><tpages>4</tpages></addata></record> |
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| language | eng |
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| source | MEDLINE; Elsevier ScienceDirect Journals Complete |
| subjects | Animals Biological and medical sciences Chicken Chickens Clonidine - pharmacology Clonidine HCl Dose-Response Relationship, Drug Drug Interactions Eating - drug effects Esters - pharmacology Feeding behavior Feeding. Feeding behavior Female Fundamental and applied biological sciences. Psychology l- NG-nitro-arginine methyl ester HCl (LNNA) Male Nitric oxide Nitric Oxide - pharmacology Vertebrates: anatomy and physiology, studies on body, several organs or systems |
| title | The interaction of clonidine and nitric oxide on feeding behavior in the chicken |
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