Improving sensitivity for serodiagnosis of tuberculosis using TB16.3-echA1 fusion protein

Summary This study aimed at developing and assessing the fusion proteins with enhanced sensitivity to detect antibodies in plasma as a diagnostic method for tuberculosis. DNA fragments encoding TB16.3 and echA1 gene regions corresponding to proteins TB16.3 and echA1 from Mycobacterium tuberculosis w...

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Veröffentlicht in:	Tuberculosis (Edinburgh, Scotland) Scotland), 2014-09, Vol.94 (5), p.519-524
Hauptverfasser:	Khurshid, Sana, Afzal, Madeeha, Khalid, Ruqyya, Khan, Imran H, Akhtar, M. Waheed
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antibodies, Bacterial - blood Antigens, Bacterial - chemistry Antigens, Bacterial - genetics Bacterial Proteins - chemistry Bacterial Proteins - genetics Biomarkers - blood Case-Control Studies Cloning, Molecular Enzyme-Linked Immunosorbent Assay Humans Infectious Disease Models, Molecular Mycobacterium tuberculosis - genetics Mycobacterium tuberculosis - immunology Predictive Value of Tests Protein Conformation Pulmonary/Respiratory Rabbits Recombinant Fusion Proteins - chemistry Recombinant Fusion Proteins - genetics Reproducibility of Results Serologic Tests - methods Tuberculosis, Pulmonary - blood Tuberculosis, Pulmonary - diagnosis Tuberculosis, Pulmonary - immunology
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