Differences in the Tumorigenic Activity of a Pure Hydrocarbon and a Complex Mixture following Ingestion: Benzo[a]pyrene vs Manufactured Gas Plant Residue

The tumorigenic activity of manufactured gas plant residue (MGP) was evaluated in female A/J mice using a F0927 basal gel diet system. Adulterated diets containing MGP (0.10% or 0.25%) or benzo[a]pyrene (B[alpha]P; 16 or 98 ppm) were fed for 260 days. A negative control group was maintained on a non...

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