Review and expert opinion in age related macular degeneration. Focus on the pathophysiology, angiogenesis and pharmacological and clinical data

Age related macular degeneration (AMD) is a pathological aging of the macula, brought about by the interaction of genetic and environmental factors. It induces geographic atrophy of the retina and/or choroidal neovascularization. In the latter, abnormal vessels develop from the choriocapillaris, wit...

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Veröffentlicht in:	Journal francais d'ophtalmologie 2014-09, Vol.37 (7), p.566-579
Hauptverfasser:	Weber, M, Sennlaub, F, Souied, E, Cohen, S-Y, Béhar-Cohen, F, Milano, G, Tadayoni, R
Format:	Artikel
Sprache:	fre
Schlagworte:	Aging - physiology Angiogenesis Inhibitors - therapeutic use Antibodies, Monoclonal, Humanized - therapeutic use Bevacizumab Choroidal Neovascularization - drug therapy Drug Tolerance Humans Macular Degeneration - drug therapy Macular Degeneration - physiopathology Randomized Controlled Trials as Topic Ranibizumab Receptors, Vascular Endothelial Growth Factor - antagonists & inhibitors Receptors, Vascular Endothelial Growth Factor - therapeutic use Recombinant Fusion Proteins - therapeutic use Retina - physiology Risk Factors Vascular Endothelial Growth Factor A - antagonists & inhibitors
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