Effect of O super(6)-methylguanine-DNA methyltransferase gene activity on repair in human cells transformed by a regulatable ada) gene

To assess the biological role of DNA methylation at the O super(6) position of guanine (O super(6)MeG) a human cell line was created that contains a regulatable gene of the O super(6)MeG-DNA methyl-transferase (MT), a repair activity that removes O super(6)MeG adducts from the DNA. MT-deficient HeLa...

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Veröffentlicht in:	Carcinogenesis (New York) 1990-01, Vol.11 (1), p.21-26
1. Verfasser:	Waldstein, E A
Format:	Artikel
Sprache:	eng
Schlagworte:	DNA DNA methyltransferase DNA repair methylation
Online-Zugang:	Volltext
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